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2 型糖尿病患者睡眠质量与生活质量的相关性:一项中国的横断面研究。

Association of sleep quality and quality of life in type 2 diabetes mellitus: a cross-sectional study in China.

机构信息

Department of Control and Prevention of Chronic non-communicable diseases of Xuzhou Center for Disease Control and Prevention, Xuzhou, China.

Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.

出版信息

Diabetes Res Clin Pract. 2015 Jan;107(1):69-76. doi: 10.1016/j.diabres.2014.09.060. Epub 2014 Oct 17.

Abstract

OBJECTIVE

The aim of this study is to investigate sleep quality and quality of life, and to assess the relationship between sleep quality and quality of life in Chinese patients with type 2 diabetes mellitus (T2DM).

RESEARCH DESIGN AND METHODS

944 patients with T2DM were enrolled in our study. General characteristics and laboratory testing such as glycosylated hemoglobin A1c (HbA1c) were measured. Each patient completed a Chinese version of the Pittsburgh sleep quality index (PSQI) and the diabetes specificity quality of life scale (DSQL) questionnaires. A PSQI global score >7 was defined as poor sleep quality. A global DSQL score <40 was defined as a good quality of life. Multiple logistic regression analysis was used to examine the relationships between PSQI and DSQL.

RESULTS

Poor quality of life in participants was associated with a longer duration of diabetes, a greater number of diabetes complications, no alcohol drinking, poor glycemic control and having depression and anxiety (all P<0.001). Of the participants, 33.6% of them were poor sleepers according to their PSQI. Poor sleepers had significantly lower DSQL (P<001). After adjustment for confounders, poor sleep quality was positively associated with a lower health-related quality of life (OR: 3.67, 95% CI: 1.30-10.33, P<0.001).

CONCLUSIONS

Our results suggest that poor sleep is prevalent in T2DM and inversely associated with quality of life. It is necessary for primary health-care workers to include sleep related knowledge in diabetes self-management programs to improve sleep quality in diabetes patients.

摘要

目的

本研究旨在调查中国 2 型糖尿病(T2DM)患者的睡眠质量和生活质量,并评估睡眠质量与生活质量之间的关系。

研究设计与方法

本研究纳入了 944 例 T2DM 患者。测量了一般特征和实验室检查,如糖化血红蛋白 A1c(HbA1c)。每位患者完成了中文版匹兹堡睡眠质量指数(PSQI)和糖尿病特异性生活质量量表(DSQL)问卷。PSQI 总分>7 定义为睡眠质量差,DSQL 总分<40 定义为生活质量好。采用多因素 logistic 回归分析 PSQI 与 DSQL 之间的关系。

结果

参与者生活质量差与糖尿病病程较长、糖尿病并发症较多、不饮酒、血糖控制不佳以及抑郁和焦虑有关(均 P<0.001)。根据 PSQI,33.6%的参与者为睡眠质量差。睡眠质量差者的 DSQL 明显较低(P<001)。调整混杂因素后,睡眠质量差与健康相关生活质量较低呈正相关(OR:3.67,95%CI:1.30-10.33,P<0.001)。

结论

本研究结果表明,T2DM 患者中睡眠质量差较为常见,且与生活质量呈负相关。初级保健工作者有必要在糖尿病自我管理计划中纳入与睡眠相关的知识,以改善糖尿病患者的睡眠质量。

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