Zelman Brittany, Kiszewski Anthony, Cotter Chris, Liu Jenny
The Global Health Group, University of California San Francisco, San Francisco, CA, United States of America.
Bentley University, Waltham, MA, United States of America.
PLoS One. 2014 Dec 31;9(12):e115714. doi: 10.1371/journal.pone.0115714. eCollection 2014.
International financing for malaria increased more than 18-fold between 2000 and 2011; the largest source came from The Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund). Countries have made substantial progress, but achieving elimination requires sustained finances to interrupt transmission and prevent reintroduction. Since 2011, global financing for malaria has declined, fueling concerns that further progress will be impeded, especially for current malaria-eliminating countries that may face resurgent malaria if programs are disrupted.
This study aims to 1) assess past total and Global Fund funding to the 34 current malaria-eliminating countries, and 2) estimate their future funding needs to achieve malaria elimination and prevent reintroduction through 2030.
Historical funding is assessed against trends in country-level malaria annual parasite incidences (APIs) and income per capita. Following Kizewski et al. (2007), program costs to eliminate malaria and prevent reintroduction through 2030 are estimated using a deterministic model. The cost parameters are tailored to a package of interventions aimed at malaria elimination and prevention of reintroduction.
The majority of Global Fund-supported countries experiencing increases in total funding from 2005 to 2010 coincided with reductions in malaria APIs and also overall GNI per capita average annual growth. The total amount of projected funding needed for the current malaria-eliminating countries to achieve elimination and prevent reintroduction through 2030 is approximately US$8.5 billion, or about $1.84 per person at risk per year (PPY) (ranging from $2.51 PPY in 2014 to $1.43 PPY in 2030).
Although external donor funding, particularly from the Global Fund, has been key for many malaria-eliminating countries, sustained and sufficient financing is critical for furthering global malaria elimination. Projected cost estimates for elimination provide policymakers with an indication of the level of financial resources that should be mobilized to achieve malaria elimination goals.
2000年至2011年间,全球疟疾防治资金增长超过18倍;最大的资金来源是抗击艾滋病、结核病和疟疾全球基金(全球基金)。各国已取得重大进展,但要实现消除疟疾目标,需要持续的资金投入以阻断传播并防止疟疾重新出现。自2011年以来,全球疟疾防治资金有所下降,这引发了人们对进一步进展将受到阻碍的担忧,特别是对于当前正在消除疟疾的国家而言,如果项目中断,可能面临疟疾卷土重来的情况。
本研究旨在1)评估过去对34个当前正在消除疟疾的国家的总体资金和全球基金资金投入,以及2)估计它们到2030年实现消除疟疾并防止重新出现所需的未来资金需求。
根据国家层面疟疾年度寄生虫发病率(API)和人均收入趋势评估历史资金投入。按照Kizewski等人(2007年)的方法,使用确定性模型估计到2030年消除疟疾并防止重新出现的项目成本。成本参数针对旨在消除疟疾和防止重新出现的一系列干预措施进行了调整。
2005年至2010年期间,大多数获得全球基金支持且总体资金增加的国家,其疟疾API有所下降,人均国民总收入(GNI)年均增长率也有所下降。当前正在消除疟疾的国家到2030年实现消除疟疾并防止重新出现所需的预计资金总额约为85亿美元,即每年每高危人群约1.84美元(范围从2014年的每人每年2.51美元到2030年的每人每年1.43美元)。
尽管外部捐助资金,特别是来自全球基金的资金,对许多正在消除疟疾的国家至关重要,但持续和充足的资金对于推动全球消除疟疾至关重要。消除疟疾的预计成本估计为政策制定者提供了一个指示,表明为实现消除疟疾目标应筹集的财政资源水平。