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泰国综合内科诊所和糖尿病专科诊所2型糖尿病患者糖化血红蛋白、血压和胆固醇(ABC)控制情况的比较

Comparison of HbA1c, blood pressure, and cholesterol (ABC) control in type 2 diabetes attending general medical clinics and specialist diabetes clinics in Thailand.

作者信息

Sieng Sokha, Thinkamrop Bandit, Laohasiriwong Wongsa, Hurst Cameron

机构信息

Faculty of Public Health, Khon Kaen University, Thailand; Ministry of Education, Youth and Sport, Cambodia.

Faculty of Public Health, Khon Kaen University, Thailand.

出版信息

Diabetes Res Clin Pract. 2015 May;108(2):265-72. doi: 10.1016/j.diabres.2015.02.005. Epub 2015 Feb 16.

Abstract

AIMS

The aim of this study was to compare the achievement of clinical targets for patients with type 2 diabetes mellitus (T2DM) in general medical clinics (GMCs) and specialist diabetes clinics (SDCs) for different hospital types (regional, provincial and community) in Thailand.

METHODS

We used the medical records of patients (n=26,860) with T2DM from 595 hospitals (26 regional, 70 provincial and 499 community) across all 77 provinces in Thailand. Generalized linear mixed models were used to conduct multi-level modeling to evaluate the achievement of individual outcomes (A - glycated hemoglobin (HbA1c) <7.0% (53 mmol/mol), B - Blood Pressure (BP) <140/80 mmHg and C - LDL-Cholesterol <100mg/dL) and aggregated outcomes (AllABC - achieved all three of the targets, AnyABC - achieved at least one target, ABCcount - the number of targets achieved: 0, 1, 2 or 3).

RESULTS

Neither clinic types (SDCs or GMCs) were consistency superior across all hospital types. For regional hospitals, SDCs were associated with higher odds of achieving BP, AnyABC, and ABCcount (OR=1.55, 95%CI: 1.25-1.92, p<0.001; OR=1.35, 95%CI: 1.02-1.79; p=0.04; RR=1.10, 95%CI: 1.01-1.20, p=0.03, respectively). For provincial hospitals, SDCs exhibited higher achievement of BP and LDL-C (OR=1.52, 95%CI: 1.23-1.87, p<0.001; OR=1.28, 95%CI: 1.04-1.58, p=0.02, respectively). For community hospitals, however GMCs demonstrated higher achievement of BP and AnyABC (OR=0.81, 95%CI: 0.67-0.98, p=0.03; OR=0.74, 95%CI: 0.56-0.97, p=0.03, respectively).

CONCLUSIONS

In larger (regional and provincial) hospitals, SDCs outperform GMCs in several (but not all) clinical targets. In contrast, in community hospital, where most patients with T2DM are serviced, GMCs were shown to have superior performance.

摘要

目的

本研究旨在比较泰国不同类型医院(地区级、省级和社区级)的综合医疗诊所(GMC)和糖尿病专科诊所(SDC)中2型糖尿病(T2DM)患者临床指标的达成情况。

方法

我们使用了泰国77个省份595家医院(26家地区级、70家省级和499家社区级)中26,860例T2DM患者的病历。采用广义线性混合模型进行多层次建模,以评估个体指标(A - 糖化血红蛋白(HbA1c)<7.0%(53 mmol/mol)、B - 血压(BP)<140/80 mmHg和C - 低密度脂蛋白胆固醇<100mg/dL)和综合指标(AllABC - 三项指标均达标、AnyABC - 至少一项指标达标、ABCcount - 达标的指标数量:0、1、2或3)的达成情况。

结果

在所有医院类型中,诊所类型(SDC或GMC)并非始终具有优势。对于地区级医院,SDC与更高的血压达标几率、AnyABC和ABCcount相关(OR = 1.55,95%CI:1.25 - 1.92,p<0.001;OR = 1.35,95%CI:1.02 - 1.79;p = 0.04;RR = 1.10,95%CI:1.01 - 1.20,p = 0.03)。对于省级医院,SDC在血压和低密度脂蛋白胆固醇达标方面表现更高(OR分别为1.52,95%CI:1.23 - 1.87,p<0.001;OR = 1.28,95%CI:1.04 - 1.58,p = 0.02)。然而,对于社区医院,GMC在血压和AnyABC达标方面表现更高(OR分别为0.81,95%CI:0.67 - 0.98,p = 0.03;OR = 0.74,95%CI:0.56 - 0.97,p = 0.03)。

结论

在较大型(地区级和省级)医院中,SDC在一些(但并非所有)临床指标上优于GMC。相比之下,在为大多数T2DM患者提供服务的社区医院中,GMC表现更优。

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