Chabi M L, Goracci A, Roche N, Paugam A, Lupo A, Revel M P
Service de radiologie polyvalente et oncologique, groupe hospitalier de la Pitié-Salpêtrière - Charles-Foix, AP-HP, 83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
Département d'imagerie médicale, service de radiologie, IRCCS Istituto Clinico Humanitas, Via Manzoni 56, 20089 Rozzano, Italy.
Diagn Interv Imaging. 2015 May;96(5):435-42. doi: 10.1016/j.diii.2015.01.005. Epub 2015 Mar 6.
Aspergillosis is a mycotic disease usually caused by Aspergillus fumigatus, a saprophytic and ubiquitous airborne fungus. Aspergillus-related lung diseases are traditionally classified into four different forms, whose occurrence depends on the immunologic status of the host and the existence of an underlying lung disease. Allergic broncho-pulmonary aspergillosis (ABPA) affects patients with asthma or cystic fibrosis. Saprophytic infection (aspergilloma) occurs in patients with abnormal airways (chronic obstructive pulmonary disease, bronchiectasis, cystic fibrosis) or chronic lung cavities. Chronic necrotizing aspergillosis (semi-invasive form) is described in patients with chronic lung pathology or mild immunodeficiency. Invasive aspergillosis (angio-invasive or broncho-invasive forms) occurs in severely immuno-compromised patients. Knowledge of the various radiological patterns for each form, as well as the corresponding associated immune disorders and/or underlying lung diseases, helps early recognition and accurate diagnosis.
曲霉病是一种通常由烟曲霉引起的真菌病,烟曲霉是一种腐生且无处不在的空气传播真菌。曲霉相关的肺部疾病传统上分为四种不同形式,其发生取决于宿主的免疫状态和潜在肺部疾病的存在。变应性支气管肺曲霉病(ABPA)影响哮喘或囊性纤维化患者。腐生性感染(曲菌球)发生于气道异常(慢性阻塞性肺疾病、支气管扩张、囊性纤维化)或慢性肺空洞的患者。慢性坏死性曲霉病(半侵袭性形式)见于有慢性肺部病变或轻度免疫缺陷的患者。侵袭性曲霉病(血管侵袭性或支气管侵袭性形式)发生于严重免疫功能低下的患者。了解每种形式的各种放射学表现以及相应的相关免疫紊乱和/或潜在肺部疾病,有助于早期识别和准确诊断。