情绪谱系的炎症假说扩展至纤维肌痛和慢性疲劳综合征。
The inflammatory hypothesis of mood spectrum broadened to fibromyalgia and chronic fatigue syndrome.
作者信息
Dell'Osso Liliana, Bazzichi Laura, Baroni Stefano, Falaschi Valentina, Conversano Ciro, Carmassi Claudia, Marazziti Donatella
机构信息
Section of Psychiatry, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
出版信息
Clin Exp Rheumatol. 2015 Jan-Feb;33(1 Suppl 88):S109-16. Epub 2015 Mar 18.
OBJECTIVES
The present paper aimed at reviewing literature data on the inflammatory hypothesis of mood spectrum, as well as the overlapping features with some chronic rheumatologic disorders, in particular fibromyalgia and chronic fatigue syndrome.
METHODS
A literature search was carried out for English papers published in the years 2000-2014, while using the following words: mood spectrum, depression, bipolar disorders, fibromyalgia, chronic fatigue syndrome, neurotransmitters, inflammation, neuroinflammation, cytokines.
RESULTS
Overlapping features were highlighted between mood spectrum, fibromyalgia and chronic fatigue syndrome suggesting common underlying mechanisms at pathophysiological level involving both central nervous and the immune systems.
CONCLUSIONS
Taken together, the literature would suggest that the borders between different medical domains should be reconsidered in the light of common processes linking them.
目的
本文旨在综述关于情绪谱系炎症假说的文献数据，以及与某些慢性风湿性疾病（特别是纤维肌痛和慢性疲劳综合征）的重叠特征。
方法
对2000 - 2014年发表的英文论文进行文献检索，使用以下关键词：情绪谱系、抑郁症、双相情感障碍、纤维肌痛、慢性疲劳综合征、神经递质、炎症、神经炎症、细胞因子。
结果
情绪谱系、纤维肌痛和慢性疲劳综合征之间的重叠特征得到突出显示，表明在病理生理水平上存在涉及中枢神经系统和免疫系统的共同潜在机制。
结论
综合来看，文献表明应根据连接不同医学领域的共同过程重新考虑它们之间的界限。
Zotero 插件