一项随机临床试验，评估一款带有成角度刷毛新刷头的振荡旋转电动牙刷与一款具有自调节技术的市售声波牙刷在减少牙龈炎和牙菌斑方面的效果。

A randomized clinical trial evaluating gingivitis and plaque reduction of an oscillating-rotating power brush with a new brush head with angled bristles versus a marketed sonic brush with self-adjusting technology.

作者信息

Klukowska Malgorzata, Grender Julie M, Conde Erinn, Ccahuana-Vasquez Renzo Alberto, Ram Goyal C

出版信息

Am J Dent. 2014 Aug;27(4):179-84.

Abstract

PURPOSE

To compare the efficacy of an oscillating-rotating power toothbrush with a novel brush head incorporating angled CrissCross bristles (Oral-B Pro 7000 SmartSeries and Oral-B CrossAction brush head) versus a marketed sonic toothbrush (Colgate ProClinical A1500 with the Triple Clean brush head) in the reduction of gingivitis and plaque over a 6-week period.

METHODS

This was a single center, randomized, open label, examiner-blind, 2-treatment, parallel group study. Study participants who met the entrance criteria were enrolled in the study and randomly assigned to one of the two toothbrush groups. Study participants brushed with their assigned toothbrush and a marketed fluoride dentifrice for 2 minutes twice daily at home for 6 weeks. Gingivitis and plaque were evaluated at baseline and Week 6. Gingivitis was assessed using the Modified Gingival Index (MGI) and Gingival Bleeding Index (GBI) and plaque was assessed using the Rustogi Modified Navy Plaque Index (RMNPI). Data was analyzed using the ANCOVA with baseline as the covariate.

RESULTS

In total, 130 study participants were randomized to treatment resulting in 64 study participants per group completing the study. Both brushes produced statistically significant (P < 0.001) reductions in gingivitis and plaque measures relative to baseline. The oscillating-rotating,brush with the novel brush head demonstrated statistically significantly (P < 0.05) greater reductions in all gingivitis measures, as well as whole mouth and interproximal plaque measures, compared to the sonic toothbrush. The benefit for the oscillating- rotating brush over the sonic brush was 21.3% for gingivitis, 35.7% for gingival bleeding, 34.7% for number of bleeding sites, 17.4% for whole mouth plaque, and 21.2% for interproximal plaque. There were no adverse events reported or observed for either brush.

摘要

目的

比较一款配备新型成角度交错刷毛刷头的振荡旋转式电动牙刷（欧乐-B Pro 7000智能系列和欧乐-B交叉动作刷头）与一款市售声波牙刷（高露洁专业临床A1500搭配三重清洁刷头）在6周时间内减少牙龈炎和牙菌斑方面的效果。

方法

这是一项单中心、随机、开放标签、检查者盲法、双治疗、平行组研究。符合入选标准的研究参与者被纳入研究，并随机分配到两个牙刷组之一。研究参与者在家中使用分配的牙刷和市售含氟牙膏每天刷牙两次，每次2分钟，持续6周。在基线和第6周时评估牙龈炎和牙菌斑情况。使用改良牙龈指数（MGI）和牙龈出血指数（GBI）评估牙龈炎，使用鲁斯托吉改良海军牙菌斑指数（RMNPI）评估牙菌斑。以基线作为协变量，使用协方差分析对数据进行分析。

结果

共有130名研究参与者被随机分配接受治疗，每组64名研究参与者完成了研究。与基线相比，两款牙刷在牙龈炎和牙菌斑指标方面均产生了具有统计学意义（P < 0.001）的降低。与声波牙刷相比，配备新型刷头的振荡旋转式牙刷在所有牙龈炎指标以及全口和邻面牙菌斑指标方面均有统计学意义上的显著（P < 0.05）更大程度降低。振荡旋转式牙刷相对于声波牙刷在牙龈炎方面的优势为21.3%，牙龈出血方面为35.7%，出血部位数量方面为34.7%，全口牙菌斑方面为17.4%，邻面牙菌斑方面为21.2%。两款牙刷均未报告或观察到不良事件。