Metcalf C J E, Andreasen V, Bjørnstad O N, Eames K, Edmunds W J, Funk S, Hollingsworth T D, Lessler J, Viboud C, Grenfell B T
Department of Ecology and Evolutionary Biology and the Woodrow Wilson School, Princeton University, Princeton, NJ, USA.
Department of Science, Systems and Models, Universitetsvej 1, 27.1, DK-4000 Roskilde, Denmark.
Epidemics. 2015 Mar;10:11-5. doi: 10.1016/j.epidem.2014.08.004. Epub 2014 Aug 27.
Vaccination has been one of the most successful public health measures since the introduction of basic sanitation. Substantial mortality and morbidity reductions have been achieved via vaccination against many infections, and the list of diseases that are potentially controllable by vaccines is growing steadily. We introduce key challenges for modeling in shaping our understanding and guiding policy decisions related to vaccine preventable diseases.
自基本卫生设施引入以来,疫苗接种一直是最成功的公共卫生措施之一。通过针对多种感染进行疫苗接种,已大幅降低了死亡率和发病率,并且可通过疫苗预防的疾病清单正在稳步增加。我们介绍了建模在塑造我们对疫苗可预防疾病的理解并指导相关政策决策方面面临的关键挑战。