Barnabie Patricia M, Whiteley Marvin
Department of Molecular Biosciences, Institute of Cellular and Molecular Biology, Center for Infectious Disease, The University of Texas at Austin, Austin, Texas, USA.
Department of Molecular Biosciences, Institute of Cellular and Molecular Biology, Center for Infectious Disease, The University of Texas at Austin, Austin, Texas, USA
J Bacteriol. 2015 Jul;197(14):2250-1. doi: 10.1128/JB.00303-15. Epub 2015 Apr 27.
Communication is an important factor for bacterial survival, growth, and persistence. Much work has examined both inter- and intraspecies interactions and their effects on virulence. Now, researchers have begun to explore the ways in which host-modulated factors can impact bacterial interactions and subsequently affect patient outcomes. In this issue, two papers discuss how the host environment alters interactions between the pathogens Pseudomonas aeruginosa and Staphylococcus aureus, largely in the context of cystic fibrosis.
通讯是细菌生存、生长和持续存在的一个重要因素。许多研究工作都考察了种间和种内相互作用及其对毒力的影响。如今,研究人员已开始探索宿主调节因子影响细菌相互作用并进而影响患者预后的方式。在本期中,两篇论文讨论了宿主环境如何改变病原体铜绿假单胞菌和金黄色葡萄球菌之间的相互作用,主要是在囊性纤维化的背景下。