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肝硬化和肝细胞癌患者的癌症护理质量

Quality of Cancer Care in Patients with Cirrhosis and Hepatocellular Carcinoma.

作者信息

Dhanasekaran Renumathy, Talwalkar Jayant A

机构信息

Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street Southwest, Rochester, MN, 55905, USA,

出版信息

Curr Gastroenterol Rep. 2015 Sep;17(9):34. doi: 10.1007/s11894-015-0459-8.

Abstract

Hepatocellular carcinoma is the most common primary liver cancer in patients with cirrhosis and is the leading cause of mortality in these patients. Despite existence of robust clinical practice guidelines for surveillance, diagnosis, and management for hepatocellular carcinoma (HCC), the quality of care received by patients with HCC has been inconsistent. Several studies have reported disappointingly low surveillance rates in high-risk groups which likely contribute to most HCC cases being diagnosed at advanced stages. There is also data from large studies showing that significant under-referral to specialists and delay in initiation of treatment are linked to poor clinical outcomes. Given above circumstances, it is very important to perform studies which can identify areas in need of improvement in the care processes of HCC and design interventions to enhance quality of care. Unfortunately, data on validated quality indicators and quality metrics for HCC are non-existent. In this article, we review the existing literature pertaining to this issue and identify areas that need further research.

摘要

肝细胞癌是肝硬化患者中最常见的原发性肝癌,也是这些患者死亡的主要原因。尽管存在针对肝细胞癌(HCC)监测、诊断和管理的强有力的临床实践指南,但HCC患者所接受的医疗质量并不一致。多项研究报告称,高危人群的监测率低得令人失望,这可能是大多数HCC病例在晚期才被诊断出来的原因。大型研究的数据还表明,向专科医生转诊严重不足以及治疗开始延迟与不良临床结果有关。鉴于上述情况,开展能够确定HCC护理流程中需要改进的领域并设计提高护理质量的干预措施的研究非常重要。不幸的是,目前尚无关于HCC经过验证的质量指标和质量度量的数据。在本文中,我们回顾了有关该问题的现有文献,并确定了需要进一步研究的领域。

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