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老年人髋部骨折后疼痛及髋关节功能变化预测因素的前瞻性研究

Prospective study of predictive factors of changes in pain and hip function after hip fracture among the elderly.

作者信息

Orive M, Anton-Ladislao A, García-Gutiérrez S, Las Hayas C, González N, Zabala J, Quintana J M

机构信息

Research Unit, Galdakao-Usansolo Hospital, Barrio Labeaga, s/n, 48960, Usansolo, Bizkaia, Spain.

Health Services Research on Chronic Patients Network (REDISSEC), Bilbao, 48010, Bizkaia, Spain.

出版信息

Osteoporos Int. 2016 Feb;27(2):527-36. doi: 10.1007/s00198-015-3267-y. Epub 2015 Aug 5.

Abstract

UNLABELLED

Our study identified pre-fracture variables, such as home status or function, that are directly or indirectly associated with frailty status before fracture. The prevention in the deterioration of those variables would improve the prognosis of those hip fractured, being this an important issue for the societies with increasingly aging population.

INTRODUCTION

This study was designed to identify predictors of pain and declines in function among elderly patients following a fall-related hip fracture.

METHODS

Patients aged 65 or older with a fall-related hip fracture retrospectively completed pre-fracture status questionnaires (T0; n = 740) and were then prospectively followed for 6 months (T1; n = 546). Of these, 474 were randomly selected to complete an additional 18 months of follow-up (T2; n = 356). Primary outcome measures were changes in the pain and function dimensions of the Western Ontario and McMaster Universities Osteoarthritis Index questionnaire's short form (WOMAC-SF). Potential predictors included sociodemographic variables, in-hospital and clinical pre- and post-fracture data, and activities of daily living at baseline and follow-up. Multivariate logistic regression was used for analysis.

RESULTS

Predictors of worsening pain at T1 and/or T2 included living in a home care situation or nursing home before the fracture (OR at T1, 1.515; OR at T2, 2.749), and low pre-fracture pain (OR at T1, 1.028; OR at T2, 1.027). Predictors of deterioration in function at T1 and/or T2 included age ≥85 years (OR at T1, 2.714; OR at T2, 4.762), lower income (OR at T1, 1.755), high pre-fracture hip function (OR at T1, 1.029; OR at T2, 1.028), referral to rehabilitation upon discharge (OR at T1, 2.378; OR at T2, 2.881), and longer delay between fall and surgery (OR at T1, 1.133; OR at T2, 1.124).

CONCLUSIONS

Frailty before hip fracture is a predictor of greater post-fracture pain and deterioration in function. Given that exercise programs help prevent frailty, promoting exercise in elderly may improve the prognosis of hip fracture.

摘要

未标注

我们的研究确定了骨折前的变量,如家庭状况或功能,这些变量与骨折前的衰弱状态直接或间接相关。预防这些变量的恶化将改善髋部骨折患者的预后,对于人口老龄化日益严重的社会来说,这是一个重要问题。

引言

本研究旨在确定老年患者跌倒相关髋部骨折后疼痛和功能下降的预测因素。

方法

65岁及以上跌倒相关髋部骨折患者回顾性填写骨折前状态问卷(T0;n = 740),然后前瞻性随访6个月(T1;n = 546)。其中,474例被随机选择完成额外18个月的随访(T2;n = 356)。主要结局指标是西安大略和麦克马斯特大学骨关节炎指数问卷简表(WOMAC-SF)中疼痛和功能维度的变化。潜在预测因素包括社会人口统计学变量、骨折前后的住院和临床数据,以及基线和随访时的日常生活活动。采用多变量逻辑回归进行分析。

结果

T1和/或T2时疼痛加重的预测因素包括骨折前居住在家庭护理机构或养老院(T1时OR为1.515;T2时OR为2.749),以及骨折前疼痛程度低(T1时OR为1.028;T2时OR为1.027)。T1和/或T2时功能恶化的预测因素包括年龄≥85岁(T1时OR为2.714;T2时OR为4.762)、收入较低(T1时OR为1.755)、骨折前髋部功能良好(T1时OR为1.029;T2时OR为1.028)、出院后转诊至康复机构(T1时OR为2.378;T2时OR为2.881),以及跌倒与手术之间的延迟时间较长(T1时OR为1.133;T2时OR为1.124)。

结论

髋部骨折前的衰弱是骨折后疼痛加剧和功能恶化的预测因素。鉴于运动计划有助于预防衰弱,促进老年人运动可能会改善髋部骨折的预后。

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