用于检测外周动脉疾病的趾臂指数的敏感性和特异性：初步研究结果。
Sensitivity and Specificity of the Toe-Brachial Index for Detecting Peripheral Arterial Disease: Initial Findings.
作者信息
Tehan Peta, Bray Alan, Keech Ruth, Rounsley Richard, Carruthers Angela, Chuter Vivienne Helaine
机构信息
School of Health Sciences, Faculty of Health, University of Newcastle, Ourimbah, New South Wales, Australia (P.T., V.H.C.); and Vascular Health Care, Gateshead, New South Wales, Australia (A.B., R.K., R.R., A.C.).
出版信息
J Ultrasound Med. 2015 Oct;34(10):1737-43. doi: 10.7863/ultra.15.14.09071. Epub 2015 Aug 25.
OBJECTIVES
The toe-brachial index (TBI) is an alternative to the ankle-brachial index (ABI) in screening for peripheral arterial disease (PAD); however, there is limited evidence comparing their diagnostic accuracy. This study compared the diagnostic accuracy of the ABI and TBI in a population at risk of PAD.
METHODS
The sensitivity and specificity of the ABI and TBI were determined by color duplex sonography. Receiver operating characteristic (ROC) analysis was performed.
RESULTS
A total of 119 participants were recruited (75 male and 44 female). The sensitivity for PAD was highest for the TBI (71%; ABI, 45%), and the specificity was highest for the ABI (93%; TBI, 78%). Receiver operating characteristic analysis indicated that the TBI (ROC area, 0.77; P = .0001) had greater clinical efficacy for diagnosis of PAD than the ABI (ROC area, 0.65; P = .005).
CONCLUSIONS
In specific populations, the TBI may have greater clinical efficacy than the ABI for diagnosis of PAD.
目的
在筛查外周动脉疾病（PAD）时，趾臂指数（TBI）是踝臂指数（ABI）的一种替代方法；然而，比较它们诊断准确性的证据有限。本研究比较了ABI和TBI在PAD风险人群中的诊断准确性。
方法
通过彩色双功超声确定ABI和TBI的敏感性和特异性。进行了受试者操作特征（ROC）分析。
结果
共招募了119名参与者（75名男性和44名女性）。TBI对PAD的敏感性最高（71%；ABI为45%），ABI的特异性最高（93%；TBI为78%）。受试者操作特征分析表明，TBI（ROC曲线下面积，0.77；P = 0.0001）在诊断PAD方面比ABI（ROC曲线下面积，0.65；P = 0.005）具有更高的临床效能。
结论
在特定人群中，TBI在诊断PAD方面可能比ABI具有更高的临床效能。
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