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急诊科阑尾炎患儿疼痛管理中的种族差异

Racial Disparities in Pain Management of Children With Appendicitis in Emergency Departments.

作者信息

Goyal Monika K, Kuppermann Nathan, Cleary Sean D, Teach Stephen J, Chamberlain James M

机构信息

Children's National Health System, Washington, DC2Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, DC3Department of Emergency Medicine, George Washington University School of Medicine and Health Sc.

Department of Emergency Medicine, University of California Davis School of Medicine, Sacramento5Department of Pediatrics, University of California Davis School of Medicine, Sacramento.

出版信息

JAMA Pediatr. 2015 Nov;169(11):996-1002. doi: 10.1001/jamapediatrics.2015.1915.

Abstract

IMPORTANCE

Racial disparities in use of analgesia in emergency departments have been previously documented. Further work to understand the causes of these disparities must be undertaken, which can then help inform the development of interventions to reduce and eradicate racial disparities in health care provision.

OBJECTIVE

To evaluate racial differences in analgesia administration, and particularly opioid administration, among children diagnosed as having appendicitis.

DESIGN, SETTING, AND PARTICIPANTS: Repeated cross-sectional study of patients aged 21 years or younger evaluated in the emergency department who had an International Classification of Diseases, Ninth Revision diagnosis of appendicitis, using the National Hospital Ambulatory Medical Care Survey from 2003 to 2010. We calculated the frequency of both opioid and nonopioid analgesia administration using complex survey weighting. We then performed multivariable logistic regression to examine racial differences in overall administration of analgesia, and specifically opioid analgesia, after adjusting for important demographic and visit covariates, including ethnicity and pain score.

MAIN OUTCOMES AND MEASURES

Receipt of analgesia administration (any and opioid) by race.

RESULTS

An estimated 0.94 (95% CI, 0.78-1.10) million children were diagnosed as having appendicitis. Of those, 56.8% (95% CI, 49.8%-63.9%) received analgesia of any type; 41.3% (95% CI, 33.7%-48.9%) received opioid analgesia (20.7% [95% CI, 5.3%-36.0%] of black patients vs 43.1% [95% CI, 34.6%-51.4%] of white patients). When stratified by pain score and adjusted for ethnicity, black patients with moderate pain were less likely to receive any analgesia than white patients (adjusted odds ratio = 0.1 [95% CI, 0.02-0.8]). Among those with severe pain, black patients were less likely to receive opioids than white patients (adjusted odds ratio = 0.2 [95% CI, 0.06-0.9]). In a multivariable model, there were no significant differences in the overall rate of analgesia administration by race. However, black patients received opioid analgesia significantly less frequently than white patients (12.2% [95% CI, 0.1%-35.2%] vs 33.9% [95% CI, 0.6%-74.9%], respectively; adjusted odds ratio = 0.2 [95% CI, 0.06-0.8]).

CONCLUSIONS AND RELEVANCE

Appendicitis pain is undertreated in pediatrics, and racial disparities with respect to analgesia administration exist. Black children are less likely to receive any pain medication for moderate pain and less likely to receive opioids for severe pain, suggesting a different threshold for treatment.

摘要

重要性

先前已有文献记载急诊科在镇痛药物使用方面存在种族差异。必须开展进一步工作以了解这些差异的成因,这有助于为制定减少和消除医疗保健提供方面种族差异的干预措施提供依据。

目的

评估诊断为阑尾炎的儿童在镇痛药物使用,尤其是阿片类药物使用方面的种族差异。

设计、地点和参与者:对21岁及以下在急诊科接受评估且国际疾病分类第九版诊断为阑尾炎的患者进行重复横断面研究,数据来自2003年至2010年的国家医院门诊医疗调查。我们使用复杂抽样权重计算阿片类和非阿片类镇痛药物的使用频率。然后,在调整重要人口统计学和就诊协变量(包括种族和疼痛评分)后,进行多变量逻辑回归分析,以研究在镇痛药物总体使用,特别是阿片类镇痛药物使用方面的种族差异。

主要结局和指标

按种族划分的镇痛药物使用情况(任何类型和阿片类)。

结果

估计有94万(95%可信区间,78万 - 110万)儿童被诊断为阑尾炎。其中,56.8%(95%可信区间,49.8% - 63.9%)接受了任何类型的镇痛治疗;41.3%(95%可信区间,33.7% - 48.9%)接受了阿片类镇痛治疗(黑人患者为20.7% [95%可信区间, 5.3% - 36.0%],白人患者为43.1% [95%可信区间, 34.6% - 51.4%])。按疼痛评分分层并调整种族因素后,中度疼痛的黑人患者比白人患者接受任何镇痛治疗的可能性更小(调整后的优势比 = 0.1 [95%可信区间, 0.02 - 0.8])。在重度疼痛患者中,黑人患者比白人患者接受阿片类药物治疗的可能性更小(调整后的优势比 = 0.2 [95%可信区间, 0.06 - 0.9])。在多变量模型中,不同种族在镇痛药物总体使用频率上没有显著差异。然而,黑人患者接受阿片类镇痛治疗的频率明显低于白人患者(分别为12.2% [95%可信区间, 0.1% - 35.2%] 和33.9% [95%可信区间, 0.6% - 74.9%];调整后的优势比 = 0.2 [95%可信区间, 0.06 - 0.8])。

结论及意义

儿科阑尾炎疼痛治疗不足,且在镇痛药物使用方面存在种族差异。黑人儿童中度疼痛时接受任何止痛药物治疗的可能性较小,重度疼痛时接受阿片类药物治疗的可能性也较小,这表明治疗阈值不同。

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