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羟考酮治疗成人癌症疼痛。

Oxycodone for Cancer Pain in Adult Patients.

机构信息

National Collaborating Centre for Cancer, Wales, United Kingdom.

Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom.

出版信息

JAMA. 2015;314(12):1282-3. doi: 10.1001/jama.2015.8556.

Abstract

CLINICAL QUESTION

Is oxycodone associated with greater efficacy and fewer adverse events compared with alternative analgesics for cancer pain?

BOTTOM LINE

Oxycodone was not associated with superior cancer pain relief or fewer adverse effects compared with other strong opioids, such as morphine or oxymorphone. However, the quality of the evidence was low.

摘要

临床问题

与其他用于治疗癌痛的镇痛剂相比,羟考酮的疗效是否更好,且不良反应更少?

结论

与其他强阿片类药物(如吗啡或羟吗啡酮)相比,羟考酮并未显示出在缓解癌痛或减少不良反应方面的优势。然而,证据质量较低。

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