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美国纽约奥尔巴尼室内空气中双酚、双酚 A 二缩水甘油醚 (BADGEs) 和 novolac 缩水甘油醚 (NOGEs) 的出现及其对吸入暴露的影响。

Occurrence of bisphenols, bisphenol A diglycidyl ethers (BADGEs), and novolac glycidyl ethers (NOGEs) in indoor air from Albany, New York, USA, and its implications for inhalation exposure.

机构信息

Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Albany, NY 12201, United States.

Center for Disease Control and Prevention of Yangtze River Administration and Navigational Affairs, General Hospital of the Yangtze River Shipping, Wuhan 430019, China.

出版信息

Chemosphere. 2016 May;151:1-8. doi: 10.1016/j.chemosphere.2016.02.038. Epub 2016 Mar 15.

Abstract

Bisphenols, bisphenol A diglycidyl ethers (BADGEs), and novolac glycidyl ethers (NOGEs) are used in the production of epoxy resins and polycarbonate plastics. Despite the widespread application of these chemicals in household products, studies on their occurrence in indoor air are limited. In this study, 83 indoor air samples were collected in 2014 from various locations in Albany, New York, USA, to determine the concentrations of bisphenols, BADGEs (refer to BADGE and its derivatives), and NOGEs (refer to NOGE and its derivatives) and to calculate inhalation exposure to these compounds. Among eight bisphenols measured, BPA, BPF, and BPS were found in bulk air (i.e., vapor plus particulate phases), at geometric mean (GM) concentrations of 0.43, 0.69 and 0.09 ng m(-3), respectively. Among 11 BADGEs and NOGEs determined, BADGE·2H2O was the predominant compound found in indoor air (detection rate [DR]: 85.5%), at concentrations as high as 6.71 ng m(-3). Estimation of inhalation exposure to these chemicals for various age groups showed that teenagers had the highest exposure doses to BPA, BPF, BPS, and BADGE·2H2O at 5.91, 9.48, 1.24, and 3.84 ng day(-1), respectively. The body weight-normalized estimates of exposure were the highest for infants, with values at 0.24, 0.39, 0.05, and 0.16 ng kg bw(-1) day(-1) for BPA, BPF, BPS, and BADGE·2H2O, respectively. This is the first survey to report inhalation exposure to bisphenols, BADGEs, and NOGEs.

摘要

双酚类物质、双酚 A 二缩水甘油醚(BADGEs)和 novolac 缩水甘油醚(NOGEs)被用于生产环氧树脂和聚碳酸酯塑料。尽管这些化学物质广泛应用于家用产品,但有关其在室内空气中存在情况的研究却很有限。在这项研究中,于 2014 年从美国纽约州奥尔巴尼的不同地点采集了 83 个室内空气样本,以确定双酚类物质、BADGEs(BADGE 及其衍生物)和 NOGEs(NOGE 及其衍生物)的浓度,并计算这些化合物的吸入暴露量。在所测量的 8 种双酚类物质中,BPA、BPF 和 BPS 存在于空气本体(即气相和颗粒相)中,几何平均值(GM)浓度分别为 0.43、0.69 和 0.09ng/m3。在所确定的 11 种 BADGEs 和 NOGEs 中,BADGE·2H2O 是室内空气中主要的化合物(检出率 [DR]:85.5%),浓度高达 6.71ng/m3。对不同年龄组吸入这些化学物质的暴露量进行估算表明,青少年对 BPA、BPF、BPS 和 BADGE·2H2O 的暴露剂量最高,分别为 5.91、9.48、1.24 和 3.84ng/day。体重归一化的暴露估计值在婴儿中最高,BPA、BPF、BPS 和 BADGE·2H2O 的暴露值分别为 0.24、0.39、0.05 和 0.16ng/kg bw/day。这是首次报告双酚类物质、BADGEs 和 NOGEs 的吸入暴露情况。

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