Röhrig Gabriele
Ageing Clinical Research, Department II of Internal Medicine, University Hospital Cologne, Cologne, Germany; Department of Geriatrics, St Marien Hospital Cologne, Cologne, Germany.
Clin Interv Aging. 2016 Mar 17;11:319-26. doi: 10.2147/CIA.S90727. eCollection 2016.
Anemia and frailty are two common findings in geriatric patients and have been shown to be associated with poor outcomes in this patient group. Recent studies have contributed to the growing evidence of a possible association with the age-related chronic inflammatory status known as "inflammaging". These findings do not only give a better insight into the pathogenesis of anemia in frailty, but also offer new treatment options. The present article focuses on this assumed association between anemia, frailty, and inflammaging and summarizes current management options for anemia in frail patients.
贫血和虚弱是老年患者中两个常见的表现,并且已被证明与该患者群体的不良预后相关。最近的研究为与称为“炎症衰老”的年龄相关慢性炎症状态可能存在关联提供了越来越多的证据。这些发现不仅能更好地洞察虚弱状态下贫血的发病机制,还提供了新的治疗选择。本文重点关注贫血、虚弱和炎症衰老之间的这种假定关联,并总结了虚弱患者贫血的当前管理方案。