延寿药物：是否到了付诸实践的时候？

Longevity-Promoting Pharmaceuticals: Is it a Time for Implementation?

机构信息

Laboratory of Epigenetics, Institute of Gerontology, Kiev, Ukraine.

ReGenera Research Group for Aging-Intervention and Montenapoleone Medical Center, Healthy Aging Unit, Milano, Italy.

出版信息

Trends Pharmacol Sci. 2016 May;37(5):331-333. doi: 10.1016/j.tips.2016.02.003.

DOI:10.1016/j.tips.2016.02.003

PMID:27113007

Abstract

Recent experimental studies demonstrate that medications targeting aging (antioxidants, calorie restriction mimetics, autophagy inductors, etc.) can substantially promote health and extend lifespan. Pharmacologically targeting aging appears to be more effective in preventing age-related pathology compared with treatments targeted to particular pathologies. The development of new antiaging drugs represents a great opportunity for the pharmaceutical and healthcare industries.

摘要

最近的实验研究表明，针对衰老的药物（抗氧化剂、热量限制类似物、自噬诱导剂等）可以显著促进健康并延长寿命。与针对特定疾病的治疗相比，药理学靶向衰老似乎更能有效地预防与年龄相关的病理。新型抗衰老药物的开发为制药和医疗保健行业提供了巨大的机会。