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MOCAT2:一种宏基因组组装、注释和分析框架。

MOCAT2: a metagenomic assembly, annotation and profiling framework.

作者信息

Kultima Jens Roat, Coelho Luis Pedro, Forslund Kristoffer, Huerta-Cepas Jaime, Li Simone S, Driessen Marja, Voigt Anita Yvonne, Zeller Georg, Sunagawa Shinichi, Bork Peer

机构信息

Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany School of Biotechnology and Biomolecular Sciences, University of New South Wales, 2052 Sydney, Australia.

出版信息

Bioinformatics. 2016 Aug 15;32(16):2520-3. doi: 10.1093/bioinformatics/btw183. Epub 2016 Apr 8.

Abstract

UNLABELLED

MOCAT2 is a software pipeline for metagenomic sequence assembly and gene prediction with novel features for taxonomic and functional abundance profiling. The automated generation and efficient annotation of non-redundant reference catalogs by propagating pre-computed assignments from 18 databases covering various functional categories allows for fast and comprehensive functional characterization of metagenomes.

AVAILABILITY AND IMPLEMENTATION

MOCAT2 is implemented in Perl 5 and Python 2.7, designed for 64-bit UNIX systems and offers support for high-performance computer usage via LSF, PBS or SGE queuing systems; source code is freely available under the GPL3 license at http://mocat.embl.de

CONTACT

: bork@embl.de

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

未标注

MOCAT2是一个用于宏基因组序列组装和基因预测的软件流程,具有用于分类学和功能丰度分析的新特性。通过从涵盖各种功能类别的18个数据库传播预先计算的注释来自动生成和高效注释非冗余参考目录,从而实现宏基因组的快速全面功能表征。

可用性和实现方式

MOCAT2用Perl 5和Python 2.7实现,针对64位UNIX系统设计,并通过LSF、PBS或SGE排队系统支持高性能计算机使用;源代码可在GPL3许可下从http://mocat.embl.de免费获取。

联系方式

bork@embl.de

补充信息

补充数据可在《生物信息学》在线获取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf1/4978931/7e9a7ac86b58/btw183f1p.jpg

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