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三级医疗中心晚期糖尿病患者的并发症:一项基于回顾性登记的研究。

Complications in Advanced Diabetics in a Tertiary Care Centre: A Retrospective Registry-Based Study.

作者信息

Dias Amit, Gomes Edwin, Dessai Ankush

机构信息

Project Co-ordinator, Goa Medical College , Bambolim, Goa, India .

Assistant Professor, Department of Preventive and Social Medicine, Goa Medical College , Bambolim, Goa, India .

出版信息

J Clin Diagn Res. 2016 Apr;10(4):OC15-9. doi: 10.7860/JCDR/2016/15268.7583. Epub 2016 Apr 1.

Abstract

INTRODUCTION

Diabetes is a major public health problem in our country and complications of diabetes are a major cause of morbidity and mortality. There is a need to quantify the complications in order to improve our strategies for prevention and management.

AIM

To measure the prevalence of complications in type 2 diabetics following up at a tertiary care centre and to study its association with the socio-demographic and clinical parameters.

MATERIALS AND METHODS

A retrospective record based study was conducted on 3261 type 2 diabetic patients on insulin therapy, recorded in the diabetic registry maintained at Goa Medical College from Aug 2009 to May 2012. Data on anthropometric measurements, demographic characteristics, complications and other details were extracted from these records.

RESULTS

Out of the 3261 patients 1025 (31.4%) had macrovascular complications and 1122 (34.4%) had at least one microvascular complication. The prevalence of peripheral vascular disease, coronary artery disease and stroke were 6.7%, 21.3% and 6.6% respectively and were significantly higher in males. The prevalence of diabetic retinopathy, nephropathy and neuropathy were 16.7%, 16.5% and 16.3% respectively with diabetic nephropathy being significantly higher in males. Trend analysis showed significant association of rising prevalence of all complications with age (p<0.05). Duration of diabetes also showed significantly positive trend for all complications (p<0.05) except stroke.

CONCLUSION

The study presents the prevalence of diabetic complications in patients reporting to a tertiary hospital in Goa. Coronary artery disease was found to be the most common complication. As age and duration of diabetes were found to be significantly associated, efforts should be made towards promoting earlier diagnosis of diabetes so as to improve management and decrease the chances of complications.

摘要

引言

糖尿病是我国一个主要的公共卫生问题,糖尿病并发症是发病和死亡的主要原因。有必要对并发症进行量化,以改进我们的预防和管理策略。

目的

测量在一家三级医疗中心接受随访的2型糖尿病患者并发症的患病率,并研究其与社会人口统计学和临床参数的关联。

材料与方法

对2009年8月至2012年5月在果阿医学院维持的糖尿病登记册中记录的3261例接受胰岛素治疗的2型糖尿病患者进行了一项基于回顾性记录的研究。从这些记录中提取了人体测量、人口统计学特征、并发症及其他详细信息的数据。

结果

在3261例患者中,1025例(31.4%)有大血管并发症,1122例(34.4%)至少有一种微血管并发症。外周血管疾病、冠状动脉疾病和中风的患病率分别为6.7%、21.3%和6.6%,男性患病率显著更高。糖尿病视网膜病变、肾病和神经病变的患病率分别为16.7%、16.5%和16.3%,糖尿病肾病男性患病率显著更高。趋势分析显示所有并发症患病率的上升与年龄显著相关(p<0.05)。糖尿病病程除中风外,对所有并发症也显示出显著的正相关趋势(p<0.05)。

结论

该研究呈现了在果阿一家三级医院就诊的患者中糖尿病并发症的患病率。发现冠状动脉疾病是最常见的并发症。由于发现年龄和糖尿病病程显著相关,应努力促进糖尿病的早期诊断,以改善管理并降低并发症的发生几率。

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