毒理学中系统评价的出现
The Emergence of Systematic Review in Toxicology.
作者信息
Stephens Martin L, Betts Kellyn, Beck Nancy B, Cogliano Vincent, Dickersin Kay, Fitzpatrick Suzanne, Freeman James, Gray George, Hartung Thomas, McPartland Jennifer, Rooney Andrew A, Scherer Roberta W, Verloo Didier, Hoffmann Sebastian
机构信息
Johns Hopkins Center for Alternatives to Animal Testing, Baltimore, Maryland
Freelance Science and Technology Writer, Takoma Park, Maryland.
出版信息
Toxicol Sci. 2016 Jul;152(1):10-6. doi: 10.1093/toxsci/kfw059. Epub 2016 May 5.
The Evidence-based Toxicology Collaboration hosted a workshop on "The Emergence of Systematic Review and Related Evidence-based Approaches in Toxicology," on November 21, 2014 in Baltimore, Maryland. The workshop featured speakers from agencies and organizations applying systematic review approaches to questions in toxicology, speakers with experience in conducting systematic reviews in medicine and healthcare, and stakeholders in industry, government, academia, and non-governmental organizations. Based on the workshop presentations and discussion, here we address the state of systematic review methods in toxicology, historical antecedents in both medicine and toxicology, challenges to the translation of systematic review from medicine to toxicology, and thoughts on the way forward. We conclude with a recommendation that as various agencies and organizations adapt systematic review methods, they continue to work together to ensure that there is a harmonized process for how the basic elements of systematic review methods are applied in toxicology.
循证毒理学协作组织于2014年11月21日在马里兰州巴尔的摩举办了一场关于“毒理学中系统评价及相关循证方法的兴起”的研讨会。研讨会的发言者包括来自应用系统评价方法解决毒理学问题的机构和组织的人员、在医学和医疗保健领域进行系统评价有经验的人员，以及来自行业、政府、学术界和非政府组织的利益相关者。基于研讨会的报告和讨论，我们在此阐述毒理学中系统评价方法的现状、医学和毒理学的历史先例、系统评价从医学向毒理学转化面临的挑战，以及对未来发展方向的思考。我们最后建议，随着各机构和组织采用系统评价方法，它们应继续共同努力，确保在毒理学中应用系统评价方法基本要素的过程保持协调一致。
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