伊朗克尔曼阿夫扎利普尔医院收治的儿童美沙酮中毒的诱发因素
Predisposing Factors for Methadone Poisoning in Children Hospitalized at Kerman Afzalipour Hospital, Iran.
作者信息
Hosseininasab Ali, Vahidi Aliasghar, Bagheri-Charouk Fatemeh
机构信息
Associate Professor, Afzalipour Hospital Clinical Research Center AND Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Associate Professor, Department of Pediatrics, School of Medicine AND Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran.
出版信息
Addict Health. 2016 Winter;8(1):61-6.
BACKGROUND
Methadone is a synthetic opioid that has been used to relieve severe pain in addiction withdrawal. Unfortunately, due to non-standard supply and storage, the incidence of poisoning and deaths caused by this drug is increasing daily. The purpose of this study was to determine the underlying causes of methadone poisoning in children admitted to Kerman Afzalipour Hospital, Kerman University of Medical Sciences, Iran, during 2012.
METHODS
This cross-sectional study was performed on 105 children diagnosed with methadone poisoning and admitted to the pediatric emergency ward at Kerman Afzalipour Hospital. The required information was recorded through interviews with parents, patient examination, and if necessary telephone calls with the parents. The data were analyzed using SPSS software.
FINDINGS
Mean age of children was 3.9 ± 2.4 years and 59.0% of them were boys. Most parents had a high school diploma or a lower level of education. In all cases, a family member or relative, or at least one person in a party they attended was an addict. In most cases, methadone was fed to the child by mistake instead of water or other drugs. Parental substance abuse, employment status, and family income were significantly associated with methadone poisoning.
CONCLUSION
Training of methadone storage in individuals who need to use this drug can help to prevent accidental ingestion and poisoning of children.
背景
美沙酮是一种合成阿片类药物，已被用于缓解成瘾戒断时的剧痛。不幸的是，由于供应和储存不规范，该药物导致的中毒和死亡发生率日益上升。本研究的目的是确定2012年期间伊朗克尔曼医科大学克尔曼阿夫扎利普尔医院收治的儿童美沙酮中毒的潜在原因。
方法
本横断面研究对105名被诊断为美沙酮中毒并入住克尔曼阿夫扎利普尔医院儿科急诊病房的儿童进行。所需信息通过与家长访谈、患者检查以及必要时与家长电话沟通来记录。数据使用SPSS软件进行分析。
结果
儿童的平均年龄为3.9±2.4岁，其中59.0%为男孩。大多数家长拥有高中文凭或更低的教育水平。在所有病例中，家庭成员或亲属，或他们参加的聚会中的至少一人是吸毒者。在大多数情况下，美沙酮是误喂给儿童的，而非水或其他药物。父母的药物滥用、就业状况和家庭收入与美沙酮中毒显著相关。
结论
对需要使用该药物的人员进行美沙酮储存培训有助于预防儿童意外摄入和中毒。
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