Bilderbeck Amy C, Atkinson Lauren Z, McMahon Hannah C, Voysey Merryn, Simon Judit, Price Jonathan, Rendell Jennifer, Hinds Chris, Geddes John R, Holmes Emily, Miklowitz David J, Goodwin Guy M
University Department of Psychiatry, University of Oxford, Oxford, UK.
Nuffield Department of Primary Care Health Sciences, University of Oxford, UK.
J Affect Disord. 2016 Nov 15;205:245-251. doi: 10.1016/j.jad.2016.06.064. Epub 2016 Jul 6.
Psychoeducation is an effective adjunct to medications in bipolar disorder (BD). Brief psychoeducational approaches have been shown to improve early identification of relapse. However, the optimal method of delivery of psychoeducation remains uncertain. Here, our objective was to compare a short therapist-facilitated vs. self-directed psychoeducational intervention for BD.
BD outpatients who were receiving medication-based treatment were randomly assigned to 5 psychoeducation sessions administered by a therapist (Facilitated Integrated Mood Management; FIMM; n=60), or self-administered psychoeducation (Manualized Integrated Mood Management; MIMM; n=61). Follow-up was based on patients' weekly responses to an electronic mood monitoring programme over 12 months.
Over follow-up, there were no group differences in weekly self-rated depression symptoms or relapse/readmission rates. However, knowledge of BD (assessed with the Oxford Bipolar Knowledge questionnaire (OBQ)) was greater in the FIMM than the MIMM group at 3 months. Greater illness knowledge at 3 months was related to a higher proportion of weeks well over 12 months.
Features of the trial may have reduced the sensitivity to our psychoeducation approach, including that BD participants had been previously engaged in self-monitoring.
Improved OBQ score, while accelerated by a short course of therapist-administered psychoeducation (FIMM), was seen after both treatments. It was associated with better outcome assessed as weeks well. When developing and testing a new psychosocial intervention, studies should consider proximal outcomes (e.g., acquired knowledge) and their short-term impact on illness course in bipolar disorder.
心理教育是双相情感障碍(BD)药物治疗的有效辅助手段。简短的心理教育方法已被证明可改善复发的早期识别。然而,心理教育的最佳实施方式仍不确定。在此,我们的目的是比较由治疗师引导的简短心理教育干预与自我指导的心理教育干预对双相情感障碍的效果。
接受药物治疗的双相情感障碍门诊患者被随机分配到由治疗师进行的5次心理教育课程(引导式综合情绪管理;FIMM;n = 60),或自我管理的心理教育(手册化综合情绪管理;MIMM;n = 61)。随访基于患者在12个月内对电子情绪监测程序的每周反馈。
在随访期间,两组在每周自评抑郁症状或复发/再入院率方面没有差异。然而,在3个月时,FIMM组对双相情感障碍的知识了解程度(通过牛津双相情感障碍知识问卷(OBQ)评估)高于MIMM组。3个月时更高的疾病知识水平与12个月内状态良好周数的比例更高有关。
该试验的特点可能降低了对我们心理教育方法敏感性,包括双相情感障碍参与者之前已参与自我监测。
两种治疗后均观察到,尽管由治疗师实施的简短心理教育课程(FIMM)加速了OBQ评分的改善,但它与以状态良好周数评估的更好结果相关。在开发和测试新的社会心理干预措施时,研究应考虑近端结果(如获得的知识)及其对双相情感障碍病程的短期影响。