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人格障碍患者的自杀风险与自杀方式

Suicide risk and suicide method in patients with personality disorders.

作者信息

Björkenstam Charlotte, Ekselius Lisa, Berlin Marie, Gerdin Bengt, Björkenstam Emma

机构信息

Department of Clinical Neurosciences, Division of Insurance Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, USA; Department of Sociology, Stockholm University, Stockholm, Sweden.

Department of Neuroscience, Psychiatry, Uppsala University, Uppsala, Sweden.

出版信息

J Psychiatr Res. 2016 Dec;83:29-36. doi: 10.1016/j.jpsychires.2016.08.008. Epub 2016 Aug 12.

Abstract

OBJECTIVE

The influence of psychopathology on suicide method has revealed different distributions among different psychiatric disorders. However, evidence is still scarce. We hypothesized that having a diagnosis of personality disorder (PD) affect the suicide method, and that different PD clusters would influence the suicide method in different ways. In addition, we hypothesized that the presence of psychiatric and somatic co-morbidity also affects the suicide method.

METHOD

We examined 25,217 individuals aged 15-64 who had been hospitalized in Sweden with a main diagnosis of PD the years 1987-2013 (N = 25,217). The patients were followed from the date of first discharge until death or until the end of the follow-up period, i.e. December 31, 2013, for a total of 323,508.8 person-years, with a mean follow up time of 11.7 years. The SMR, i.e. the ratio between the observed number of suicides and the expected number of suicides, was used as a measure of risk.

RESULTS

Overall PD, different PD-clusters, and comorbidity influenced the suicide method. Hanging evidenced highest SMR in female PD patients (SMR 34.2 (95% CI: 29.3-39.8)), as compared to non-PD patients and jumping among male PD patients (SMR 24.8 (95% CI: 18.3-33.6)), as compared to non PD-patients. Furthermore, the elevated suicide risk was related to both psychiatric and somatic comorbidity.

CONCLUSION

The increased suicide risk was unevenly distributed with respect to suicide method and type of PD. However, these differences were only moderate and greatly overshadowed by the overall excess suicide risk in having PD. Any attempt from society to decrease the suicide rate in persons with PD must take these characteristics into account.

摘要

目的

精神病理学对自杀方式的影响在不同精神障碍中呈现出不同的分布。然而,相关证据仍然匮乏。我们假设人格障碍(PD)的诊断会影响自杀方式,并且不同的PD类别会以不同方式影响自杀方式。此外,我们假设精神和躯体共病的存在也会影响自杀方式。

方法

我们研究了1987年至2013年期间在瑞典住院、主要诊断为PD的25217名15 - 64岁个体(N = 25217)。患者从首次出院之日起被随访至死亡或随访期结束,即2013年12月31日,总计323508.8人年,平均随访时间为11.7年。标准化死亡比(SMR),即观察到的自杀人数与预期自杀人数之比,被用作风险衡量指标。

结果

总体PD、不同的PD类别以及共病均影响自杀方式。与非PD患者相比,女性PD患者中上吊的SMR最高(SMR 34.2(95%可信区间:29.3 - 39.8)),与非PD患者相比,男性PD患者中跳楼的SMR最高(SMR 24.8(95%可信区间:18.3 - 33.6))。此外,自杀风险升高与精神和躯体共病均相关。

结论

自杀风险的增加在自杀方式和PD类型方面分布不均。然而,这些差异仅为中等程度,且被患有PD的总体过高自杀风险所掩盖。社会上任何降低PD患者自杀率的尝试都必须考虑到这些特征。

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