Gryn-Rynko Anna, Bazylak Grzegorz, Olszewska-Slonina Dorota
Department of Pharmaco-Bromatology & Molecular Nutrition, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Department of Pharmaco-Bromatology & Molecular Nutrition, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Biomed Pharmacother. 2016 Dec;84:628-636. doi: 10.1016/j.biopha.2016.09.081. Epub 2016 Sep 30.
The present work demonstrates the profound and unique phyto-pharmacological and nutritional profile of white mulberry (Morus alba L.) leaves which containing considerable amounts of easy digestive proteins, carbohydrates, micro- and macronutrients, polyphenols, free amino acids, organic acids. The wide range of significant biopharmaceutical activities of the aqueous and polar organic solvents extracts from mulberry leaves - including antidiabetic, antibacterial, anticancer, cardiovascular, hypolipidemic, antioxidant, antiatherogenic, and anti-inflammatory - have been critically discussed. The main objective was to demonstrate the results of recently published study on the components of white mulberry leaves exhibiting their biological activity in the various pathological and health human ailments. In addition, we intend to drawn the attention of researchers and public health workers for the extended exploration of this deciduous plant leaves as the source of potential indigenous nutraceuticals and functional food products to enable development of alternative prevention and treatment protocols offered in therapy of the common non-communicable diseases and malignances.
目前的研究表明,白桑叶具有深刻而独特的植物药理学和营养特性,其中含有大量易于消化的蛋白质、碳水化合物、微量和常量营养素、多酚、游离氨基酸、有机酸。本文对桑叶水提取物和极性有机溶剂提取物的广泛显著生物制药活性进行了批判性讨论,这些活性包括抗糖尿病、抗菌、抗癌、心血管、降血脂、抗氧化、抗动脉粥样硬化和抗炎等。主要目的是展示最近发表的关于白桑叶成分在各种人类病理和健康疾病中表现出生物活性的研究结果。此外,我们希望引起研究人员和公共卫生工作者的注意,以便进一步探索这种落叶植物的叶子,将其作为潜在的本土营养保健品和功能性食品的来源,从而开发出替代的预防和治疗方案,用于常见非传染性疾病和恶性肿瘤的治疗。