Koul P A, Hakim N A, Malik S A, Khan U H, Patel J, Gnatiuc L, Burney P G J
Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India.
National Heart & Lung Institute (NHLI), Imperial College, London, UK.
Int J Tuberc Lung Dis. 2016 Oct;20(10):1399-1404. doi: 10.5588/ijtld.15.0968.
Data on spirometrically defined chronic airflow limitation (CAL) are scarce in developing countries.
To estimate the prevalence of spirometrically defined CAL in Kashmir, North India.
Using Burden of Obstructive Lung Disease survey methods, we administered questionnaires to randomly selected adults aged ⩾40 years. Post-bronchodilator spirometry was performed to estimate the prevalence of CAL and its relation to potential risk factors.
Of 1100 participants initially recruited, 953 (86.9%) responded and 757 completed acceptable spirometry and questionnaires. The prevalence of a forced expiratory volume in 1 s/forced vital capacity (FEV/FVC) ratio less than the lower limit of normal was 17.3% (4.5) in males and 14.8% (2.1) in females. Risk factors for CAL included higher age, cooking with wood and lower educational status. The prevalence of current smoking was 61% in males and 22% in females; most smoked hookahs. CAL was found equally in non-smoking males and females, and was independently associated with the use of the hookah, family history of respiratory disease and poor education. A self-reported doctor's diagnosis of chronic obstructive pulmonary disease was reported in 8.4/1000 (0.9% of females and 0.8% of males).
Spirometrically confirmed CAL is highly prevalent in Indian Kashmir, and seems to be related to the high prevalence of smoking, predominantly in the form of hookah smoking.
发展中国家关于肺量计定义的慢性气流受限(CAL)的数据稀缺。
评估印度北部克什米尔地区肺量计定义的CAL的患病率。
采用慢性阻塞性肺疾病负担调查方法,我们向随机选取的年龄≥40岁的成年人发放问卷。进行支气管扩张剂后肺量测定以评估CAL的患病率及其与潜在危险因素的关系。
最初招募的1100名参与者中,953人(86.9%)做出回应,757人完成了可接受的肺量测定和问卷。1秒用力呼气容积/用力肺活量(FEV/FVC)比值低于正常下限的患病率在男性中为17.3%(4.5),在女性中为14.8%(2.1)。CAL的危险因素包括年龄较大、用木柴做饭和教育程度较低。当前吸烟者的患病率在男性中为61%,在女性中为22%;大多数人吸的是水烟。CAL在不吸烟的男性和女性中同样存在,并且与吸用水烟、呼吸系统疾病家族史和教育程度低独立相关。每1000人中有8.4人(女性为0.9%,男性为0.8%)自我报告医生诊断为慢性阻塞性肺疾病。
肺量计确诊的CAL在印度克什米尔地区高度流行,并且似乎与吸烟的高患病率有关,主要是水烟吸烟形式。