A fast-responsive fluorescent probe based on BODIPY dye for sensitive detection of hypochlorite and its application in real water samples.

Hypochlorite serves as a powerful antimicrobial agent in human immune system, the detection of which is of great significance. Herein a novel fluorescent probe based on BODIPY dye and diaminomaleonitrile has been synthesized and characterized to sense hypochlorite. The fluorescence of the system is dramatically enhanced by ClO due to the removal of C=N isomerization effect in physiological pH condition. The complete reaction only needs a few seconds, which enables the probe to facilitate real-time detection. This probe also has satisfactory selectivity for ClO even in the presence of other interferential ions and shows high sensitivity with a detection limit of 19.8nM. Furthermore, Probe 1 has been successfully applied to detect ClO in real water samples.