波斯尼亚和黑塞哥维那弓形虫感染的首次报告：献血者研究。

First Report on Toxoplasma gondii Infection in Bosnia and Herzegovina: Study in Blood Donors.

作者信息

Bobić Branko, Milosavić Milanka, Guzijan Gordana, Djurković-Djaković Olgica

机构信息

1 National Reference Laboratory for Toxoplasmosis, Center of Excellence for Food- and Vector-borne Zoonoses, Institute for Medical Research, University of Belgrade , Belgrade, Serbia .

2 Institute for Transfusion Medicine of the Republic of Srpska , Banja Luka, Bosnia and Herzegovina.

出版信息

Vector Borne Zoonotic Dis. 2016 Dec;16(12):807-809. doi: 10.1089/vbz.2016.2028. Epub 2016 Oct 31.

DOI:10.1089/vbz.2016.2028

PMID:27797684

Abstract

AIM

To provide the first data on the prevalence and basic demographic risk factors for human Toxoplasma gondii infection in the Banja Luka region, Bosnia and Herzegovina (B&H).

METHODS

Analysis of serological and epidemiological data in a series of 320 blood donors (aged 18-55 years) from the Banja Luka region tested for Toxoplasma infection in February 2015.

RESULTS

The overall prevalence of infection was 30.6% (95% confidence interval [CI] 25.5-35.6). The risk factors included male gender (odds ratio [OR] = 1.69; 95% CI = 1.02-2.79), increasing age (OR = 1.37; 95% CI = 1.09-1.72), and living in rural area (OR = 1.83; 95% CI = 1.10-3.05). The prevalence of infection significantly increased with age and was higher in males and in residents of rural areas. Among women, the risk factor was the residence area (OR = 2.39; 95% CI = 1.08-5.30), whereas among men, it was age (OR = 1.45; 95% CI = 1.07-1.95). In the subgroup of women of childbearing age (aged 18-45 years), the prevalence was 22.3% (95% CI = 14.9-29.7).

CONCLUSION

This study provided the first data on the prevalence of Toxoplasma infection in B&H, as well as insight into the demographic risk factors as a basis for a future prevention program for Toxoplasma infection.

摘要

目的

提供波斯尼亚和黑塞哥维那（波黑）巴尼亚卢卡地区人类弓形虫感染患病率及基本人口统计学风险因素的首批数据。

方法

对2015年2月在巴尼亚卢卡地区接受弓形虫感染检测的320名献血者（年龄18 - 55岁）的血清学和流行病学数据进行分析。

结果

总体感染率为30.6%（95%置信区间[CI] 25.5 - 35.6）。风险因素包括男性（优势比[OR] = 1.69；95% CI = 1.02 - 2.79）、年龄增长（OR = 1.37；95% CI = 1.09 - 1.72）以及居住在农村地区（OR = 1.83；95% CI = 1.10 - 3.05）。感染率随年龄显著增加，男性和农村地区居民的感染率更高。在女性中，风险因素是居住地区（OR = 2.39；95% CI = 1.08 - 5.30），而在男性中，是年龄（OR = 1.45；95% CI = 1.07 - 1.95）。在育龄妇女（年龄18 - 45岁）亚组中，患病率为22.3%（95% CI = 14.9 - 29.7）。