Patterson P Daniel, Smith Kenneth J, Hostler David
Department of Emergency Medicine, University of Pittsburgh School of Medicine, 3600 Forbes Avenue, Iroquois Bldg., Suite 400A, Pittsburgh, PA, 15261, USA.
Section of Decision Sciences, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
BMC Cardiovasc Disord. 2016 Nov 21;16(1):229. doi: 10.1186/s12872-016-0414-0.
The leading cause of death among firefighters in the United States (U.S.) is cardiovascular events (CVEs) such as sudden cardiac arrest and myocardial infarction. This study compared the cost-effectiveness of three strategies to prevent CVEs among firefighters.
We used a cost-effectiveness analysis model with published observational and clinical data, and cost quotes for physiologic monitoring devices to determine the cost-effectiveness of three CVE prevention strategies. We adopted the fire department administrator perspective and varied parameter estimates in one-way and two-way sensitivity analyses.
A wellness-fitness program prevented 10% of CVEs, for an event rate of 0.9% at $1440 over 10-years, or an incremental cost-effectiveness ratio of $1.44 million per CVE prevented compared to no program. In one-way sensitivity analyses, monitoring was favored if costs were < $116/year. In two-way sensitivity analyses, monitoring was not favored if cost was ≥ $399/year. A wellness-fitness program was not favored if its preventive relative risk was >0.928.
Wellness-fitness programs may be a cost-effective solution to preventing CVE among firefighters compared to real-time physiologic monitoring or doing nothing.
在美国,消防员的主要死因是心血管事件(CVE),如心脏骤停和心肌梗死。本研究比较了三种预防消防员CVE策略的成本效益。
我们使用了一个成本效益分析模型,结合已发表的观察性和临床数据以及生理监测设备的成本报价,来确定三种CVE预防策略的成本效益。我们采用消防部门管理人员的视角,并在单向和双向敏感性分析中改变参数估计。
一项健康-健身计划可预防10%的CVE,10年内事件发生率为0.9%,成本为1440美元,与无计划相比,每预防一例CVE的增量成本效益比为144万美元。在单向敏感性分析中,如果成本低于每年116美元,则倾向于监测。在双向敏感性分析中,如果成本≥每年399美元,则不倾向于监测。如果其预防相对风险>0.928,则不倾向于采用健康-健身计划。
与实时生理监测或不采取任何措施相比,健康-健身计划可能是预防消防员CVE的一种具有成本效益的解决方案。