大鼠适应游泳负荷过程中的氧化平衡

Oxidative Balance in Rats during Adaptation to Swimming Load.

作者信息

Elikov A V

机构信息

Department of Chemistry, Kirov State Medical Academy, Ministry of Healthcare of the Russian Federation, Kirov, Russia.

出版信息

Bull Exp Biol Med. 2016 Dec;162(2):180-183. doi: 10.1007/s10517-016-3570-4. Epub 2016 Dec 2.

DOI:10.1007/s10517-016-3570-4

PMID:27909966

Abstract

The main parameters of free radical oxidation and antioxidant defense in the blood plasma, erythrocytes, and homogenates of skeletal muscles, heart, liver, lungs, and kidneys were studied in adult outbred albino male rats with different degree of adaptation to moderate exposure to swimming. The rats were trained to swim regularly over 1 month. Changes in oxidative balance varied in organs and tissues and depended on the level of training. Malonic dialdehyde content in the erythrocytes after swimming increased by 13.8% in non-trained animals, but decreased by 19.2% in trained rats. Parameters of blood plasma reflect the general oxidative balance of organs and tissues.

摘要

在成年远交系白化雄性大鼠中，研究了血浆、红细胞以及骨骼肌、心脏、肝脏、肺和肾脏匀浆中自由基氧化和抗氧化防御的主要参数，这些大鼠对适度游泳暴露具有不同程度的适应性。大鼠经过1个月的定期游泳训练。氧化平衡的变化在各器官和组织中有所不同，并取决于训练水平。未训练的动物游泳后红细胞中的丙二醛含量增加了13.8%，而训练过的大鼠则下降了19.2%。血浆参数反映了器官和组织的总体氧化平衡。