Lim Ying Jye, Rosita Jamaluddin, Chieng Jin Yu, Hazizi Abu Saad
Department of Nutrition & Dietetics, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, UPM Serdang, Selangor Darul Ehsan, Malaysia.
Department of Medicine, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, UPM Serdang, Selangor Darul Ehsan, Malaysia.
PLoS One. 2016 Dec 20;11(12):e0167243. doi: 10.1371/journal.pone.0167243. eCollection 2016.
Functional constipation is very common with heterogeneous symptoms that have substantial impact on patient quality of life as well as medical resources which are rarely reported as life-threatening. The aim of this study is to examine the prevalence and symptoms characteristic of functional constipation (FC) by using Rome III diagnostic criteria among tertiary education students with an intention to introduce treatment in the future.
Demographic, socio-economics characteristics and symptoms of FC using the Rome III criteria were sought using a questionnaire administered to Malaysian students in a tertiary education setting. Other data obtained were the general health status, lifestyle factors and anthropometric measurements. Using a simple random sampling method, a total of 1662 students were recruited in the study with a response rate of 95.0%. Sampled data are presented as frequency and percentage and stratified accordingly into categories for Chi-square analysis.
The prevalence of functional constipation among the students was 16.2%, with a significantly higher prevalence among women (17.4%) than men (12.5%). Hard or lumpy stool, incomplete evacuation, anorectal obstruction and straining were reported as the commonest symptoms experienced. Type 3 was the most frequent stool consistency experienced among the constipated individuals (35.2%). Only 4.4% of individuals reported having less than three defecations per week. Using univariable analysis, FC was significantly associated with sex (odds ratio: 1.48, 95% CI: 1.06-2.06) and age group (odds ratio: 1.34, 95% CI: 1.01-1.79) with P value < 0.05 significance level. In multivariate logistic regression analysis, only sex was found significantly associated with FC (adjusted odds ratio: 1.53, 95% CI: 1.08-2.17, P < 0.05).
Based on the prevalence rate, constipation is a common problem among tertiary education students (16.2%), with significantly more prevalence among the female respondents. Early detection of symptoms and further intervention studies focusing on treatment recommendation in improving the symptoms are essential.
功能性便秘非常常见,其症状具有异质性,对患者生活质量以及医疗资源都有重大影响,不过很少被报道有生命危险。本研究旨在采用罗马Ⅲ诊断标准,调查高等院校学生中功能性便秘(FC)的患病率及症状特征,以便未来引入治疗措施。
通过对马来西亚高等院校学生进行问卷调查,收集其人口统计学、社会经济特征以及使用罗马Ⅲ标准的功能性便秘症状。获取的其他数据包括一般健康状况、生活方式因素和人体测量数据。采用简单随机抽样方法,共招募了1662名学生参与研究,应答率为95.0%。抽样数据以频率和百分比形式呈现,并相应分层进行卡方分析。
学生中功能性便秘的患病率为16.2%,女性患病率(17.4%)显著高于男性(12.5%)。硬便或块状便、排便不尽、肛门直肠阻塞感和排便费力被报告为最常见的症状。在便秘个体中,3型大便质地最为常见(35.2%)。只有4.4%的个体报告每周排便少于3次。单因素分析显示,功能性便秘与性别(比值比:1.48,95%置信区间:1.06 - 2.06)和年龄组(比值比:1.34,95%置信区间:1.01 - 1.79)显著相关,P值<0.05。多因素逻辑回归分析中,仅发现性别与功能性便秘显著相关(调整后比值比:1.53,95%置信区间:1.08 - 2.17,P<0.05)。
基于患病率,便秘是高等院校学生中的常见问题(16.2%),女性受访者中的患病率显著更高。早期发现症状以及针对改善症状的治疗建议进行进一步干预研究至关重要。