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运用新型生物电阻抗分析技术评估中国社区老年人肌肉减少症的患病率

Estimation of prevalence of sarcopenia by using a new bioelectrical impedance analysis in Chinese community-dwelling elderly people.

作者信息

Wang Hui, Hai Shan, Cao Li, Zhou Jianghua, Liu Ping, Dong Bi-Rong

机构信息

Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, China.

School of Clinical Medicine, Chengdu Medical College, Chengdu, China.

出版信息

BMC Geriatr. 2016 Dec 28;16(1):216. doi: 10.1186/s12877-016-0386-z.

Abstract

BACKGROUND

The aim of the present study was to validate the usefulness of the new octapolar multifrequency bioelectrical impedance analysis (BIA) for assessment of appendicular skeletal muscle mass (ASM) by comparing it with that of dual-energy X-ray absorptiometry (DXA) and to investigate the prevalence of sarcopenia in Chinese community-dwelling elderly according to Asian Working Group for Sarcopenia (AWGS) definition.

METHODS

A cross-sectional study was conducted in communities of Chengdu, China. A total of 944 community-dwelling elderly adults aged ≥60 years were included. ASM was measured by using DXA as a criterion method to validate a standing eight-electrode multifrequency BIA (InBody 720), followed by a further estimation of the prevalence of sarcopenia according the AWGS definition.

RESULTS

In the Bland-Altman analysis, no significant difference was found between DXA and BIA based on the ASM measurements. The prevalence of AWGS-defined sarcopenia was 12.5% in the elderly women and 8.2% in the elderly men.

CONCLUSIONS

BIA is suitable for body composition monitoring (ASM) in elderly Chinese as a fast, noninvasive, and convenient method; therefore, it may be a better choice in large epidemiological studies in the Chinese population. The prevalence of AWGS-defined sarcopenia was approximately 10.4% and increased with age in the Chinese community-dwelling elderly in this study.

摘要

背景

本研究的目的是通过将新型八极多频生物电阻抗分析(BIA)与双能X线吸收法(DXA)进行比较,验证其在评估四肢骨骼肌质量(ASM)方面的有效性,并根据亚洲肌少症工作组(AWGS)的定义调查中国社区居住老年人中肌少症的患病率。

方法

在中国成都的社区进行了一项横断面研究。共纳入944名年龄≥60岁的社区居住老年人。以DXA作为标准方法测量ASM,以验证站立式八电极多频BIA(InBody 720),随后根据AWGS定义进一步估计肌少症的患病率。

结果

在Bland-Altman分析中,基于ASM测量,DXA和BIA之间未发现显著差异。AWGS定义的肌少症患病率在老年女性中为12.5%,在老年男性中为8.2%。

结论

BIA作为一种快速、无创且便捷的方法,适用于中国老年人的身体成分监测(ASM);因此,在针对中国人群的大型流行病学研究中,它可能是一个更好的选择。在本研究中,AWGS定义的肌少症患病率约为10.4%,且在中国社区居住老年人中随年龄增长而增加。

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