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低速肢体枪伤的感染率与治疗

Infection Rates and Treatment of Low-Velocity Extremity Gunshot Injuries.

作者信息

Nguyen Mai P, Savakus Jonathan C, OʼDonnell Jeffrey A, Prayson Nicholas F, Reich Michael S, Golob Joseph F, McDonald Amy A, Como John J, Vallier Heather A

机构信息

MetroHealth System, Case Western Reserve University, Cleveland, OH.

出版信息

J Orthop Trauma. 2017 Jun;31(6):326-329. doi: 10.1097/BOT.0000000000000827.

Abstract

OBJECTIVES

To determine the rates of infection in low-energy gunshot wounds (GSWs) to the extremity.

DESIGN

Retrospective review.

SETTING

Level I trauma center.

PATIENTS/PARTICIPANTS: Patients (N = 140) with at least 90-day follow-up for extremity-only low-energy GSW injuries from 2010-2014 were retrospectively reviewed. Treatment was recorded, including type and duration of antibiotics and details of nonoperative and operative managements.

MAIN OUTCOME MEASURES

The rates of superficial and deep infections.

RESULTS

The overall infection rate was 15.7% (22 patients), and the deep infection rate was 3.6% (5 patients). Age, sex, and injury location were similar between the groups that did and did not receive antibiotic prophylaxis. Injury Severity Scores were higher in the group that did receive antibiotics. Regarding soft tissue-only injuries, antibiotic prophylaxis trended toward a lower rate of overall infection versus no antibiotic prophylaxis (6.1% vs. 25.9%, respectively, P = 0.07). Multiple doses of antibiotics did not reduce the rate of infection when compared with a single dose (14.6% vs. 12.5%, respectively, P = 1.00). No deep infections occurred in patients with nonoperatively treated fractures, regardless of antibiotic administration. All operatively treated fractures received antibiotic prophylaxis and demonstrated superficial and deep infection rates of 15.1% and 5.7%, respectively.

CONCLUSIONS

Infections after low-energy extremity GSWs are infrequent. For soft tissue injuries without fracture, a single dose of intravenous antibiotics in the emergency department was associated with a lower rate of infection compared with no antibiotics. Operatively treated low-energy GSW fractures should receive standard perioperative antibiotics.

LEVEL OF EVIDENCE

Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.

摘要

目的

确定四肢低能量枪伤(GSW)的感染率。

设计

回顾性研究。

地点

一级创伤中心。

患者/参与者:对2010年至2014年期间仅累及四肢的低能量GSW损伤且至少随访90天的患者(N = 140例)进行回顾性研究。记录治疗情况,包括抗生素的类型和使用时间以及非手术和手术治疗的细节。

主要观察指标

浅表和深部感染率。

结果

总体感染率为15.7%(22例患者),深部感染率为3.6%(5例患者)。接受和未接受抗生素预防的两组患者在年龄、性别和损伤部位方面相似。接受抗生素治疗的组损伤严重程度评分更高。对于仅软组织损伤,与未使用抗生素预防相比(分别为6.1%和25.9%,P = 0.07),抗生素预防的总体感染率有降低趋势。与单剂量抗生素相比,多剂量抗生素并未降低感染率(分别为14.6%和12.5%,P = 1.00)。非手术治疗的骨折患者无论是否使用抗生素均未发生深部感染。所有接受手术治疗的骨折患者均接受了抗生素预防,浅表和深部感染率分别为15.1%和5.7%。

结论

四肢低能量GSW后的感染并不常见。对于无骨折的软组织损伤,与不使用抗生素相比,在急诊科单次静脉注射抗生素与较低的感染率相关。接受手术治疗的四肢低能量GSW骨折应接受标准的围手术期抗生素治疗。

证据水平

预后IV级。有关证据水平的完整描述,请参阅作者指南。

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