Krishnamurthy Gautham, Singh Harjeet, Rajendran Jayapal, Sharma Vishal, Yadav Thakur Deen, Gaspar Balan Louis, Vasishta Rakesh Kumar, Singh Rajinder
Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical, Education and Research, Chandigarh 160012, India.
Ther Adv Infect Dis. 2016 Dec;3(6):152-157. doi: 10.1177/2049936116678589. Epub 2016 Dec 1.
Gallbladder tuberculosis, in an endemic region, is a common infectious etiology affecting a rare organ. The high prevalence of carcinoma gallbladder in the endemic regions of tuberculosis, like India, poses diagnostic dilemma.
We are reporting three cases of gallbladder tuberculosis mimicking carcinoma gallbladder of which the first two cases were operated with a presumptive diagnosis of malignancy. The third case presented to us after laparoscopic cholecystectomy elsewhere and on evaluation was found to have disseminated tuberculosis.
The lack of pathognomonic clinical and radiological characters results in histological surprise of gallbladder tuberculosis following surgery performed for other indications like malignancy. In preoperatively diagnosed patients medical management plays pivotal role in management. Surgery is required in symptomatic patients. On the other hand, histologically proven cases following surgical resection require antitubercular therapy.
Previous history of tuberculosis or concomitant tuberculosis at other sites may provide clue to the diagnosis of biliary tuberculosis. Antitubercular treatment after surgery plays an important role in preventing further dissemination.
在地方病流行地区,胆囊结核是一种影响罕见器官的常见感染病因。在结核病流行地区,如印度,胆囊癌的高发病率带来了诊断难题。
我们报告了三例疑似胆囊癌的胆囊结核病例,其中前两例在初步诊断为恶性肿瘤后进行了手术。第三例在其他地方接受腹腔镜胆囊切除术后前来就诊,经评估发现患有播散性结核。
缺乏特征性的临床和放射学表现导致在因其他指征(如恶性肿瘤)进行手术后,胆囊结核出现组织学上的意外情况。在术前诊断的患者中,药物治疗在管理中起关键作用。有症状的患者需要手术治疗。另一方面,手术切除后经组织学证实的病例需要抗结核治疗。
既往结核病史或其他部位同时存在结核可能为胆管结核的诊断提供线索。术后抗结核治疗在预防进一步播散方面起着重要作用。