Hegde John V, Chen Allen M, Chin Robert K
Department of Radiation Oncology, University of California, Los Angeles, David Geffen School of Medicine, 200 UCLA Medical Plaza, Suite B265, Los Angeles, CA 90095, USA.
Department of Radiation Oncology, University of California, Los Angeles, David Geffen School of Medicine, 200 UCLA Medical Plaza, Suite B265, Los Angeles, CA 90095, USA.
Otolaryngol Clin North Am. 2017 Aug;50(4):755-764. doi: 10.1016/j.otc.2017.03.011. Epub 2017 May 17.
Treatment of squamous cell carcinoma of the head and neck is rapidly evolving due to changing patient populations, an emphasis on quality of life-related outcomes, and advances in radiotherapy concepts and techniques to meet these new demands. This review includes recent and ongoing studies that are potentially practice changing, including improvements in intensity-modulated radiotherapy planning, the use of deintensified regimens in the human papilloma virus-related setting, and adjuvant therapy after transoral robotic surgery. Additionally, recent studies of modern proton therapy are reviewed.
由于患者群体的变化、对生活质量相关结果的重视以及放射治疗概念和技术的进步以满足这些新需求,头颈部鳞状细胞癌的治疗正在迅速发展。本综述包括近期和正在进行的可能改变临床实践的研究,包括调强放射治疗计划的改进、在人乳头瘤病毒相关情况下使用减强度方案以及经口机器人手术后的辅助治疗。此外,还综述了现代质子治疗的近期研究。