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肥胖症手术中阻塞性睡眠呼吸暂停的围手术期管理:共识指南。

Perioperative management of obstructive sleep apnea in bariatric surgery: a consensus guideline.

机构信息

Department of Surgery, OLVG West, Amsterdam, the Netherlands.

Department of Surgery, VU Medical Center, Amsterdam, the Netherlands.

出版信息

Surg Obes Relat Dis. 2017 Jul;13(7):1095-1109. doi: 10.1016/j.soard.2017.03.022. Epub 2017 Mar 30.

Abstract

BACKGROUND

The frequency of metabolic and bariatric surgery (MBS) is increasing worldwide, with over 500,000 cases performed every year. Obstructive sleep apnea (OSA) is present in 35%-94% of MBS patients. Nevertheless, consensus regarding the perioperative management of OSA in MBS patients is not established.

OBJECTIVES

To provide consensus based guidelines utilizing current literature and, when in the absence of supporting clinical data, expert opinion by organizing a consensus meeting of experts from relevant specialties.

SETTING

The meeting was held in Amsterdam, the Netherlands.

METHODS

A panel of 15 international experts identified 75 questions covering preoperative screening, treatment, postoperative monitoring, anesthetic care and follow-up. Six researchers reviewed the literature systematically. During this meeting, the "Amsterdam Delphi Method" was utilized including controlled acquisition of feedback, aggregation of responses and iteration.

RESULTS

Recommendations or statements were provided for 58 questions. In the judgment of the experts, 17 questions provided no additional useful information and it was agreed to exclude them. With the exception of 3 recommendations (64%, 66%, and 66% respectively), consensus (>70%) was reached for 55 statements and recommendations. Several highlights: polysomnography is the gold standard for diagnosing OSA; continuous positive airway pressure is recommended for all patients with moderate and severe OSA; OSA patients should be continuously monitored with pulse oximetry in the early postoperative period; perioperative usage of sedatives and opioids should be minimized.

CONCLUSION

This first international expert meeting provided 58 statements and recommendations for a clinical consensus guideline regarding the perioperative management of OSA patients undergoing MBS.

摘要

背景

代谢和减重手术(MBS)在全球范围内的频率正在增加,每年进行的手术超过 50 万例。阻塞性睡眠呼吸暂停(OSA)存在于 35%-94%的 MBS 患者中。然而,对于 MBS 患者 OSA 的围手术期管理尚无共识。

目的

利用当前文献并在缺乏支持临床数据的情况下,通过组织来自相关专业的专家共识会议,提供基于共识的指南。

地点

会议在荷兰阿姆斯特丹举行。

方法

一个由 15 名国际专家组成的小组确定了 75 个问题,涵盖术前筛查、治疗、术后监测、麻醉护理和随访。六名研究人员系统地审查了文献。在本次会议上,采用了“阿姆斯特丹 Delphi 法”,包括有控制地获取反馈、汇总反应和迭代。

结果

为 58 个问题提供了建议或陈述。根据专家的判断,有 17 个问题没有提供额外的有用信息,因此决定将其排除在外。除了 3 个建议(分别为 64%、66%和 66%)外,对于 55 个陈述和建议达成了共识(>70%)。一些重点包括:多导睡眠图是诊断 OSA 的金标准;建议对所有中重度 OSA 患者使用持续气道正压通气;OSA 患者在术后早期应连续监测脉搏血氧饱和度;应尽量减少围手术期镇静剂和阿片类药物的使用。

结论

这是第一次国际专家会议,就 MBS 患者围手术期 OSA 管理提供了 58 项陈述和建议,以制定临床共识指南。

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