Section of Neuro-Infectious Diseases, Rush University Medical Center, 1725 W. Harrison Street, Suite 1106, Chicago, IL, 60612, USA.
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
J Neurovirol. 2017 Oct;23(5):789-792. doi: 10.1007/s13365-017-0565-5. Epub 2017 Aug 22.
We present the case of an HIV-2-infected patient who developed progressive multifocal leukoencephalopathy (PML) in the setting of immune reconstitution inflammatory syndrome (IRIS) presenting as Bell's palsy. The brain MRI showed a single lesion in the facial colliculus considered initially to be ischemic in nature. This case report should alert clinicians that PML can occur in the setting of HIV-2 infection. It also illustrates the difficulty of establishing the diagnosis of PML.
我们报告了 1 例 HIV-2 感染患者的病例,该患者在免疫重建炎症综合征(IRIS)背景下发生进行性多灶性白质脑病(PML),表现为贝尔氏麻痹。脑部 MRI 显示面神经丘有单个病变,最初考虑为缺血性病变。本病例报告应提醒临床医生注意,PML 可发生在 HIV-2 感染的情况下。它还说明了确定 PML 诊断的困难。