Department of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
J Arthroplasty. 2018 Jan;33(1):30-35. doi: 10.1016/j.arth.2017.07.037. Epub 2017 Aug 1.
Total joint arthroplasty (TJA) is a highly successful treatment, but is burdensome to the national healthcare budget. National quality initiatives seek to reduce costly complications. Smoking's role in perioperative complication after TJA is less well known. This study aims to identify smoking's independent contribution to the risk of short-term complication after TJA.
All patients undergoing primary TJA between 2011 and 2012 were selected from the American College of Surgeon's National Surgical Quality Improvement Program's database. Outcomes of interest included rates of readmission, reoperation, mortality, surgical complications, and medical complications. To eliminate confounders between smokers and nonsmokers, a propensity score was used to generate a 1:1 match between groups.
A total of 1251 smokers undergoing TJA met inclusion criteria. Smokers in the combined total hip and knee arthroplasty cohort had higher 30-day readmission (4.8% vs 3.2%, P = .041), were more likely to have a surgical complication (odds ratio 1.84, 95% confidence interval 1.21-2.80), and had a higher rate of deep surgical site infection (SSI) (1.1% vs 0.2%, P = .007). Analysis of total hip arthroplasty only revealed that smokers had higher rates of deep SSI (1.3% vs 0.2%, P = .038) and higher readmission rate (4.3% vs 2.2%, P = .034). Analysis of total knee arthroplasty only revealed greater surgical complications (2.8% vs 1.2%, P = .048) and superficial SSI (1.8% vs 0.2%, P = .002) in smokers.
Smoking in TJA is associated with higher rates of SSI, surgical complications, and readmission.
全关节置换术(TJA)是一种非常成功的治疗方法,但给国家医疗保健预算带来了负担。国家质量倡议旨在减少昂贵的并发症。吸烟在 TJA 围手术期并发症中的作用知之甚少。本研究旨在确定吸烟对 TJA 后短期并发症风险的独立贡献。
从美国外科医师学院国家手术质量改进计划数据库中选择 2011 年至 2012 年间接受初次 TJA 的所有患者。感兴趣的结果包括再入院率、再次手术率、死亡率、手术并发症和医疗并发症。为了消除吸烟者和非吸烟者之间的混杂因素,使用倾向评分生成组间 1:1 匹配。
共有 1251 名接受 TJA 的吸烟者符合纳入标准。在全髋关节和膝关节置换术队列中,吸烟者的 30 天再入院率更高(4.8%比 3.2%,P =.041),更有可能发生手术并发症(优势比 1.84,95%置信区间 1.21-2.80),并且深部手术部位感染(SSI)发生率更高(1.1%比 0.2%,P =.007)。仅对全髋关节置换术的分析显示,吸烟者深部 SSI 发生率更高(1.3%比 0.2%,P =.038)和再入院率更高(4.3%比 2.2%,P =.034)。仅对全膝关节置换术的分析显示,吸烟者的手术并发症(2.8%比 1.2%,P =.048)和浅表 SSI(1.8%比 0.2%,P =.002)发生率更高。
TJA 中的吸烟与 SSI、手术并发症和再入院率增加有关。