酚盐对环丙烯的定向亲核加成反应。
Directed nucleophilic addition of phenoxides to cyclopropenes.
作者信息
Yamanushkin Pavel, Lu-Diaz Michael, Edwards Andrew, Aksenov Nicolai A, Rubina Marina, Rubin Michael
机构信息
Department of Chemistry, University of Kansas, 1251 Wescoe Hall Dr., Lawrence, KS 66045-7582, USA.
Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., Stavropol 355009, Russian Federation.
出版信息
Org Biomol Chem. 2017 Oct 4;15(38):8153-8165. doi: 10.1039/c7ob01785e.
Abstract
The alkali metal-templated addition of aryloxides across the double bond of non-conjugated cyclopropenes is described. High cis-selectivity is achieved through a directing effect of a strategically positioned carboxamide functionality.
摘要
描述了碱金属模板化的芳氧基化物通过非共轭环丙烯的双键加成反应。通过策略性定位的羧酰胺官能团的导向作用实现了高顺式选择性。
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