短泪膜破裂时间型干眼存在潜在的眼表异常。
Short break-up time type dry eye has potential ocular surface abnormalities.
作者信息
Ichihashi Yoshiyuki, Ide Takeshi, Kaido Minako, Ishida Reiko, Hatou Shin, Tsubota Kazuo
机构信息
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Minamiaoyama Eye Clinic, Tokyo, Japan.
出版信息
Taiwan J Ophthalmol. 2015 Apr-Jun;5(2):68-71. doi: 10.1016/j.tjo.2015.02.004. Epub 2015 May 4.
PURPOSE
To describe a case series in which corneal fluorescein staining (CFS) development occurred in short break-up time (s-BUT) dry eyes after a short period during prolonged opening of the eye.
METHODS
The study was designed as a clinical case series. Ocular surface evaluations were performed on 13 individuals with s-BUT dry eye. Tear function examinations included Schirmer's test and BUT evaluation.
RESULTS
In all 13 cases, the BUT was short, but the tear quantity was not so bad. In all cases, CFS developed following a single eye opening, and the staining was observed at sites that showed as dark spots. In several cases, the CFS disappeared later.
CONCLUSION
In this study, we demonstrated that CFS could develop following a single eye opening. Based on our findings, CFS is a dynamic phenomenon rather than a stable indicator of ocular surface abnormalities. Moreover, s-BUT dry eye has the potential to show ocular surface abnormalities.
目的
描述一系列病例，其中在短泪膜破裂时间（s-BUT）的干眼患者中，长时间睁眼后短时间内出现了角膜荧光素染色（CFS）。
方法
本研究设计为临床病例系列。对13例s-BUT干眼患者进行眼表评估。泪液功能检查包括泪液分泌试验和泪膜破裂时间评估。
结果
所有13例患者的泪膜破裂时间均较短，但泪液量尚可。所有病例在单次睁眼后均出现角膜荧光素染色，且染色出现在显示为黑点的部位。在几例病例中，角膜荧光素染色后来消失了。
结论
在本研究中，我们证明了单次睁眼后可出现角膜荧光素染色。基于我们的发现，角膜荧光素染色是一种动态现象，而非眼表异常的稳定指标。此外，短泪膜破裂时间的干眼有出现眼表异常的可能。
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