日本 2 型糖尿病成年患者的饮食行为与胃食管反流病患病率：Dogo 研究。

Eating Behaviours and Prevalence of Gastroesophageal Reflux Disease in Japanese Adult Patients With Type 2 Diabetes Mellitus: The Dogo Study.

机构信息

Department of Inflammatory Bowel Diseases and Therapeutics, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan.

Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan; Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Shitsukawa, Toon, Ehime, Japan.

出版信息

Can J Diabetes. 2018 Jun;42(3):308-312. doi: 10.1016/j.jcjd.2017.07.007. Epub 2017 Oct 19.

DOI:10.1016/j.jcjd.2017.07.007

PMID:29056257

Abstract

OBJECTIVES

In the general population, late-night dinner is positively associated with gastroesophageal reflux disease (GERD). No evidence exists regarding the relationship between eating behaviours and GERD in patients with type 2 diabetes mellitus, though the prevalence of GERD in patients with type 2 diabetes is higher than in those without diabetes. We conducted this study to investigate the association between eating behaviours and GERD in Japanese patients with type 2 diabetes.

METHODS

The study's subjects were 817 Japanese patients with type 2 diabetes. GERD was defined as being present when a subject had a Quality of Life and Utility Evaluation Survey Technology (QUEST) score of 4 or higher. The assessment of eating behaviour was performed by self-administered questionnaire. Subjects were considered positive for late-night dinner if they answered yes to the question "Do you eat dinner within 2 hours before bedtime at least 3 times per week?

RESULTS

The prevalence values of GERD, skipping breakfast, bedtime snacking, late-night dinner and fast eating were 32.0%, 13.7%, 27.1%, 28.8%, and 44.4%, respectively. Late-night dinner was independently positively associated with GERD in patients with type 2 diabetes; the adjusted odds ratio was 1.46 (95% CI 1.03 to 2.05). No relationships were found between skipping breakfast, bedtime snacking or fast eating and GERD.

CONCLUSIONS

Late-night dinner may be positively associated with GERD in Japanese patients with type 2 diabetes.

摘要

目的

在普通人群中，深夜晚餐与胃食管反流病（GERD）呈正相关。尽管 2 型糖尿病患者中 GERD 的患病率高于无糖尿病患者，但关于饮食行为与 2 型糖尿病患者 GERD 之间的关系尚无证据。我们进行这项研究旨在调查日本 2 型糖尿病患者饮食行为与 GERD 之间的关系。

方法

本研究的对象是 817 名日本 2 型糖尿病患者。当患者的生活质量和效用评估调查技术（QUEST）评分达到 4 分或更高时，即定义为 GERD。饮食行为的评估是通过自我管理问卷进行的。如果患者每周至少 3 次在睡前 2 小时内回答“您是否在睡前 2 小时内吃过晚餐？”，则认为其存在深夜晚餐。

结果

GERD、不吃早餐、睡前吃零食、深夜晚餐和快速进食的患病率分别为 32.0%、13.7%、27.1%、28.8%和 44.4%。深夜晚餐与 2 型糖尿病患者的 GERD 呈独立正相关；调整后的优势比为 1.46（95%CI 1.03 至 2.05）。不吃早餐、睡前吃零食或快速进食与 GERD 之间无关系。