Cancer Discov. 2018 Jan;8(1):OF6. doi: 10.1158/2159-8290.CD-NB2017-158. Epub 2017 Nov 10.
The FDA granted accelerated approval to the second-generation BTK inhibitor acalabrutinib, which, because of its increased selectivity, seems to cause fewer side effects than ibrutinib, previously the only BTK inhibitor on the market.
美国食品药品监督管理局(FDA)加速批准了第二代布鲁顿酪氨酸激酶(BTK)抑制剂阿卡替尼,由于其选择性增强,与此前市场上唯一的BTK抑制剂伊布替尼相比,阿卡替尼似乎副作用更少。