Khera Rohan, Pandey Ambarish, Ayers Colby R, Agusala Vijay, Pruitt Sandi L, Halm Ethan A, Drazner Mark H, Das Sandeep R, de Lemos James A, Berry Jarett D
From the Division of Cardiology (R.K., A.P., C.R.A., V.A., M.H.D., S.R.D., J.A.d.L., J.D.B.) and Division of General Internal Medicine (S.L.P., E.A.H.), Department of Internal Medicine and Department of Clinical Sciences (E.H., J.D.B.), University of Texas Southwestern Medical Center, Dallas.
Circ Heart Fail. 2017 Nov;10(11). doi: 10.1161/CIRCHEARTFAILURE.117.004402.
To assess the current landscape of the heart failure (HF) epidemic and provide targets for future health policy interventions in Medicare, a contemporary appraisal of its epidemiology across inpatient and outpatient care settings is needed.
In a national 5% sample of Medicare beneficiaries from 2002 to 2013, we identified a cohort of 2 331 939 unique fee-for-service Medicare beneficiaries ≥65-years-old followed for all inpatient and outpatient encounters over a 10-year period (2004-2013). Preexisting HF was defined by any HF encounter during the first year, and incident HF with either 1 inpatient or 2 outpatient HF encounters. Mean age of the cohort was 72 years; 57% were women, and 86% and 8% were white and black, respectively. Within this cohort, 518 223 patients had preexisting HF, and 349 826 had a new diagnosis of HF during the study period. During 2004 to 2013, the rates of incident HF declined 32%, from 38.7 per 1000 (2004) to 26.2 per 1000 beneficiaries (2013). In contrast, prevalent (preexisting + incident) HF increased during our study period from 162 per 1000 (2004) to 172 per 1000 beneficiaries (2013) ( <0.001 for both). Finally, the overall 1-year mortality among patients with incident HF is high (24.7%) with a 0.4% absolute decline annually during the study period, with a more pronounced decrease among those diagnosed in an inpatient versus outpatient setting ( <0.001) CONCLUSIONS: In recent years, there have been substantial changes in the epidemiology of HF in Medicare beneficiaries, with a decline in incident HF and a decrease in 1-year HF mortality, whereas the overall burden of HF continues to increase.
为评估心力衰竭(HF)流行的当前情况,并为医疗保险未来的卫生政策干预提供目标,需要对其在住院和门诊护理环境中的流行病学进行当代评估。
在2002年至2013年全国5%的医疗保险受益人的样本中,我们确定了一组2331939名年龄≥65岁的独特的按服务收费的医疗保险受益人,在10年期间(2004 - 2013年)对其所有住院和门诊就诊情况进行跟踪。既往存在HF定义为第一年期间的任何HF就诊情况,以及发生1次住院或2次门诊HF就诊的新发HF。该队列的平均年龄为72岁;57%为女性,86%和8%分别为白人和黑人。在该队列中,518223名患者既往存在HF,349826名患者在研究期间有新的HF诊断。在2004年至2013年期间,新发HF的发生率下降了32%,从每1000人38.7例(2004年)降至每1000名受益人26.2例(2013年)。相比之下,在我们的研究期间,现患(既往存在 + 新发)HF从每1000人162例(2004年)增加到每1000名受益人172例(2013年)(两者均P<0.001)。最后,新发HF患者的总体1年死亡率很高(24.7%),在研究期间每年绝对下降0.4%,在住院与门诊环境中诊断的患者中下降更为明显(P<0.001)。结论:近年来,医疗保险受益人中HF的流行病学发生了重大变化,新发HF下降,1年HF死亡率降低,而HF的总体负担持续增加。