Gondek Andrea Soria, Riaza Lucia, Cuadras Daniel, Castellarnau Xavier Tarrado, Krauel Lucal
Department of Pediatric Surgery, Hospital Sant Joan de Déu, Universitat de Barcelona. Passeig Sant Joan de Déu 2, 08950 Esplugues de Llobregat, Barcelona, Spain.
Department of Pediatric Radiology, Hospital Sant Joan de Déu, Universitat de Barcelona. Passeig Sant Joan de Déu 2, 08950 Esplugues de Llobregat, Barcelona, Spain.
J Pediatr Surg. 2018 Apr;53(4):599-604. doi: 10.1016/j.jpedsurg.2017.10.050. Epub 2017 Nov 15.
BACKGROUND/PURPOSE: To identify factors that dim the efficacy of ultrasound guided saline enema (USGSE) and to design a mathematical model for predicting the probability of success of USGSE.
Retrospective review of patients admitted with the diagnosis of ileocolic intussusception from 2009 to 2014. Demographics, clinical and sonographic data were reviewed.
116 first episodes of ileocolic intussusceptions. 109 USGSE attempts were analyzed. Composite reduction rate was 77%. A significant relationship was found between initial location of the intussusception, free peritoneal fluid (OR=0.329, 95% CI: 0.124-0.875), negative Doppler signal and sonographic signs of intestinal occlusion and unsuccessful USGSE. Initial location beyond the splenic angle was an independent risk factor for USGSE failure (OR=0.053, 95% CI: 0.005-0.534). A predictive model based on onset of symptoms, free peritoneal fluid and intussusception location was a reliable tool for prediction (AUC 0.63, 95% CI: 0.53-0.817). Assuming that a patient with less than 75.3% chance of USGSE success is going to fail, we would identify more than 80.9% of the real failures.
This predictive model could be a filter selection for the patients at risk of USGSE failure and therefore candidates to further imaging investigations or referral to a surgical unit.
III.
背景/目的:确定降低超声引导下盐水灌肠(USGSE)疗效的因素,并设计一个预测USGSE成功概率的数学模型。
回顾性分析2009年至2014年诊断为回结肠套叠的住院患者。回顾人口统计学、临床和超声数据。
116例首次发作的回结肠套叠。分析了109次USGSE尝试。综合复位率为77%。发现套叠的初始位置、腹腔游离液(OR=0.329,95%CI:0.124-0.875)、多普勒信号阴性以及肠梗阻的超声征象与USGSE失败之间存在显著相关性。脾曲以外的初始位置是USGSE失败的独立危险因素(OR=0.053,95%CI:0.005-0.534)。基于症状发作、腹腔游离液和套叠位置的预测模型是一种可靠的预测工具(AUC 0.63,95%CI:0.53-0.817)。假设USGSE成功概率低于75.3%的患者将会失败,我们将识别出超过80.9%的实际失败者。
该预测模型可为有USGSE失败风险的患者进行筛选,从而确定进一步影像学检查或转诊至外科的候选者。
III级。