Children's Health and Exercise Research Centre, Sport and Health Sciences, Life and Environmental Sciences, University of Exeter, Exeter, UK.
PROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Granada, Spain; Growth, Exercise, NUtrition and Development (GENUD) Research Group, Universidad de Zaragoza, Zaragoza, Spain.
Int J Cardiol. 2018 Mar 1;254:303-309. doi: 10.1016/j.ijcard.2017.11.080. Epub 2017 Nov 26.
To examine the independent associations between physical activity (PA) intensities, sedentary time (ST), TV viewing, cardiorespiratory fitness (CRF) and muscular fitness (MF) with cardiovascular disease (CVD) risk in youth.
A cross-sectional study on 534 European adolescents (252 males, 282 females, 12.5-17.5years). Minutes per day of light (LPA), moderate (MPA) and vigorous (VPA) PA and total ST were measured using accelerometers. TV viewing time was measured using a questionnaire. CRF and MF were measured using the 20m shuttle run test and a hand dynamometer respectively. CVD outcomes included markers of body composition (body mass index (BMI), waist circumference (WC), WC/height (Ht) and sum of skinfolds (SumSF)), blood pressure, blood lipids and insulin resistance (HOMA-IR). Clustered CVD risk was calculated using SumSF, HOMA-IR, blood lipids and blood pressure.
LPA had a significant positive independent relationship with all body composition outcomes (P<0.001) and clustered CVD risk (P=0.046). VPA was negatively related to SumSF (P<0.001), BMI (P=0.018), WC/Ht (P=0.013) and clustered CVD risk (P=0.001), but was non-significant for all when other exposures were considered (P>0.10). MPA had a negative independent relationship with only WC (P=0.029) and ST was not significantly related to CVD risk (P>0.16). TV viewing had a significant positive independent relationship with HOMA-IR (P<0.001) and clustered CVD risk (P=0.019). CRF (all P<0.002) and MF (all P<0.009) had a negative independent relationship with body composition outcomes and clustered CVD risk.
Public health guidelines should prioritize on increasing levels of CRF, MF and VPA, and reducing TV viewing time to lower CVD risk in youth.
研究目的在于探讨青少年时期的身体活动(PA)强度、久坐时间(ST)、看电视时间、心肺适能(CRF)和肌肉适能(MF)与心血管疾病(CVD)风险之间的独立关联。
本研究为横断面研究,共纳入 534 名欧洲青少年(男生 252 名,女生 282 名,年龄 12.5-17.5 岁)。使用加速度计测量青少年每天的轻体力活动(LPA)、中体力活动(MPA)和高强度体力活动(VPA)时间以及总 ST。使用问卷测量青少年看电视时间。使用 20m 往返跑测试和握力计分别测量青少年的 CRF 和 MF。心血管疾病结局包括体成分标志物(体重指数(BMI)、腰围(WC)、WC/身高(Ht)和皮褶厚度总和(SumSF))、血压、血脂和胰岛素抵抗(HOMA-IR)。使用 SumSF、HOMA-IR、血脂和血压计算心血管疾病综合风险。
LPA 与所有体成分结局(P<0.001)和心血管疾病综合风险(P=0.046)均呈显著正相关。VPA 与 SumSF(P<0.001)、BMI(P=0.018)、WC/Ht(P=0.013)和心血管疾病综合风险(P=0.001)呈负相关,但当考虑其他暴露因素时,相关性均无统计学意义(P>0.10)。MPA 仅与 WC 呈负相关(P=0.029),ST 与 CVD 风险无显著相关性(P>0.16)。看电视时间与 HOMA-IR(P<0.001)和心血管疾病综合风险(P=0.019)呈显著正相关。CRF(均 P<0.002)和 MF(均 P<0.009)与体成分结局和心血管疾病综合风险呈负相关。
公共卫生指南应优先考虑提高青少年的 CRF、MF 和 VPA 水平,并减少看电视时间,以降低青少年 CVD 风险。