巨型单层囊泡上的动态蓝光可切换蛋白质图案
Dynamic blue light-switchable protein patterns on giant unilamellar vesicles.
作者信息
Bartelt S M, Chervyachkova E, Steinkühler J, Ricken J, Wieneke R, Tampé R, Dimova R, Wegner S V
机构信息
Max Planck Institute for Polymer Research, 55128, Mainz, Germany.
出版信息
Chem Commun (Camb). 2018 Jan 23;54(8):948-951. doi: 10.1039/c7cc08758f.
PMID:29319072
Abstract
The blue light-dependent interaction between the proteins iLID and Nano allows recruiting and patterning proteins on GUV membranes, which thereby capture key features of patterns observed in nature. This photoswitchable protein interaction provides non-invasive, reversible and dynamic control over protein patterns of different sizes with high specificity and spatiotemporal resolution.
摘要
蛋白质iLID和Nano之间的蓝光依赖性相互作用使得蛋白质能够在巨型单层囊泡（GUV）膜上募集并形成图案，从而捕捉到自然界中观察到的图案的关键特征。这种光开关蛋白相互作用以高特异性和时空分辨率对不同大小的蛋白质图案提供非侵入性、可逆且动态的控制。
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