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中国个体层面和地理层面社会经济地位指标与宫颈癌筛查率的显著差异:基于全国代表性调查数据集的多层次模型分析。

Significant variations in the cervical cancer screening rate in China by individual-level and geographical measures of socioeconomic status: a multilevel model analysis of a nationally representative survey dataset.

机构信息

National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Research Centre for Public Health, Tsinghua University, Beijing, China.

出版信息

Cancer Med. 2018 May;7(5):2089-2100. doi: 10.1002/cam4.1321. Epub 2018 Mar 24.

Abstract

Variations in cervical cancer screening rates in China have rarely been studied in depth. This study aimed to investigate cervical cancer screening rates in relation to both individual-level and geographical measures of socioeconomic status (SES). Data were obtained from women aged 21 years or older by face-to-face interviews between August 2013 and July 2014 as part of the Chinese Chronic Diseases and Risk Factors Surveillance. The geographical variables were obtained from the 2010 Chinese population census. The cervical cancer screening rates and 95% confidence interval (CI) were estimated and mapped. Multilevel logistic regression models were fitted. Overall, only 21.4% (95% CI: 19.6-23.1%) of 91,816 women aged ≥21 years reported having ever been screened for cervical cancer and significant geographical variations at both province and county levels were identified (P < 0.01). The cervical cancer screening rates were the lowest among the poor [13.9% (95% CI: 12.1-15.7%)], uninsured [14.4% (95% CI: 10.3-18.4%)], less-educated [16.0% (95% CI: 14.3-17.6%)], and agricultural employment [18.1% (95% CI: 15.8-20.4%)] women along with those residing in areas of low economic status [15.0% (95% CI: 11.8-18.2%)], of low urbanization [15.6% (95% CI: 13.4-17.7%)], and of low education status [16.0% (95% CI: 14.0-18.1%)]. The multilevel analysis also indicated that women with lower individual-level measures of SES residing in areas with low geographical measures of SES were significantly less likely to receive cervical cancer screening (P < 0.0001). Despite the launch of an organized cancer screening program in China, cervical cancer screening rates remain alarmingly low and significant variations based on geographical regions and measures of SES still exist. It is therefore essential to adopt strategies to better direct limited available public resources to priority groups.

摘要

中国宫颈癌筛查率的变化很少被深入研究。本研究旨在调查与个体和地理社会经济地位(SES)测量相关的宫颈癌筛查率。数据是通过 2013 年 8 月至 2014 年 7 月间的面对面访谈从 21 岁及以上的妇女中获得的,这是中国慢性病和危险因素监测的一部分。地理变量来自 2010 年中国人口普查。估计并绘制了宫颈癌筛查率及其 95%置信区间(CI)。拟合多水平逻辑回归模型。总体而言,仅 21.4%(95%CI:19.6-23.1%)的 91816 名 21 岁及以上的妇女报告曾接受过宫颈癌筛查,并且在省和县两级都发现了显著的地理差异(P<0.01)。贫困(13.9%(95%CI:12.1-15.7%))、无保险(14.4%(95%CI:10.3-18.4%))、低教育程度(16.0%(95%CI:14.3-17.6%))和农业就业(18.1%(95%CI:15.8-20.4%))的妇女以及经济地位低(15.0%(95%CI:11.8-18.2%))、城市化程度低(15.6%(95%CI:13.4-17.7%))和教育程度低(16.0%(95%CI:14.0-18.1%))地区的妇女宫颈癌筛查率最低。多水平分析还表明,处于低社会经济地位的地理区域的社会经济地位较低的妇女进行宫颈癌筛查的可能性显著降低(P<0.0001)。尽管中国已经开展了有组织的癌症筛查计划,但宫颈癌筛查率仍然低得惊人,而且基于地理区域和社会经济地位测量的差异仍然存在。因此,必须采取策略,将有限的公共资源更好地用于优先群体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cac7/5943548/5feb031edf48/CAM4-7-2089-g001.jpg

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