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甲状腺手术后出血的后果——对单一中心7805例手术的分析

Consequences of bleeding after thyroid surgery - analysis of 7805 operations performed in a single center.

作者信息

Wojtczak Beata, Aporowicz Michał, Kaliszewski Krzysztof, Bolanowski Marek

机构信息

Department and Clinic of General, Gastroenterological and Endocrine Surgery, Wroclaw Medical University, Wroclaw, Poland.

出版信息

Arch Med Sci. 2018 Mar;14(2):329-335. doi: 10.5114/aoms.2016.63004. Epub 2016 Oct 17.

Abstract

INTRODUCTION

Surgical treatment of thyroid gland diseases is associated with the possibility of severe complications. The most dangerous of them is bleeding. Current studies focus on its risk factors, rather than reoperation-related consequences.

MATERIAL AND METHODS

We analyzed 7805 thyroid operations performed from 1996 to 2014 in the Clinic of General, Gastroenterological and Endocrine Surgery of Wroclaw Medical University. Typical risk factors, symptoms and consequences of bleeding were analyzed.

RESULTS

Among operated patients 88.2% were female and 11.8% male. Bleeding occurred in 84 (1.08%) patients. Sex ( = 0.006), preoperative thyroid pathology ( = 0.03), and type of operation ( < 0.001) are significant risk factors for bleeding, while retrosternal goiter and surgeon's experience are not. Risk of bleeding is highest in the case of male sex, toxic goiter and total resection of the thyroid gland. Most reoperations took place within 6 h. In 88.8% of cases of this kind of complication the surgeon indicated the exact source of bleeding; most commonly it was the neck muscles, skin and subcutaneous tissue, or the thyroid stump. Three patients required a second reoperation, 24 suffered further complications, and 8 required transfer to the Intensive Care Unit (ICU). Cardiac arrest occurred in 3 patients and 2 suffered bilateral vocal cord palsy.

CONCLUSIONS

Bleeding after thyroid operations is a direct life threat that requires immediate intervention. As a result death may occur, half of patients suffer other complications and some require intensive care. The risk is highest in the case of male sex, toxic goiter and total resection of the thyroid gland. Each patient after thyroid surgery needs to be closely observed. An operating theatre and ICU should be available at all times.

摘要

引言

甲状腺疾病的外科治疗存在发生严重并发症的可能性。其中最危险的是出血。目前的研究集中在其危险因素上,而非再次手术相关的后果。

材料与方法

我们分析了1996年至2014年在弗罗茨瓦夫医科大学普通、胃肠和内分泌外科诊所进行的7805例甲状腺手术。分析了出血的典型危险因素、症状和后果。

结果

手术患者中88.2%为女性,11.8%为男性。84例(1.08%)患者发生出血。性别(P = 0.006)、术前甲状腺病理(P = 0.03)和手术类型(P < 0.001)是出血的重要危险因素,而胸骨后甲状腺肿和外科医生的经验则不是。男性、毒性甲状腺肿和甲状腺全切除术患者出血风险最高。大多数再次手术在6小时内进行。在88.8%的此类并发症病例中,外科医生指出了确切的出血源;最常见的是颈部肌肉、皮肤和皮下组织,或甲状腺残端。3例患者需要二次再次手术,24例出现进一步并发症,8例需要转入重症监护病房(ICU)。3例患者发生心脏骤停,2例出现双侧声带麻痹。

结论

甲状腺手术后出血直接威胁生命,需要立即干预。结果可能导致死亡,半数患者出现其他并发症,部分患者需要重症监护。男性、毒性甲状腺肿和甲状腺全切除术患者出血风险最高。甲状腺手术后的每位患者都需要密切观察。手术室和ICU应随时可用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8a9/5868671/cf420e72ed36/AMS-14-28556-g001.jpg

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