两个 AIEE 模型化合物的组装和拆卸活性及其潜在应用。
Assembly and disassembly activity of two AIEE model compounds and its potential application.
机构信息
Key Laboratory of Chemical Biology and Molecular Engineering, Ministry of Education, Institute of Molecular Science, Shanxi University, PR China.
Department of Chemistry, Shanxi University, Taiyuan, PR China.
出版信息
Talanta. 2018 Jul 1;184:394-403. doi: 10.1016/j.talanta.2018.03.007. Epub 2018 Mar 8.
Aggregation-induced emission (AIE) has received great attention. In this paper, Cu induced self-assembly and HS induced disassembly of two aggregation-induced emission enhancement (AIEE) compounds were reported in this paper. Two salicylaldehyde azine Schiff base were synthesized and characterized. It is found that 1 and 2 are AIEE active molecular both in aqueous solution and crystal state with strong yellow fluorescence. Theirs fluorescence can be selectively quenched in the presence of Cu ions with the formation of self-assembly system [1-Cu]. The interaction mechanism has been researched by multiple means. Depending on this reaction, energy changes (ΔG) from 1 to [1-Cu] was also estimated by Scatchard formula. Moreover, the quenching fluorescence was further restored by HS both in tube and live cells along with the releasing of AIEE molecular 1. That is, a reversible process between AIEE, self-assembly and disaggregation can be found in the model compound.
聚集诱导发光（AIE）受到了广泛关注。在本文中，我们报道了两种聚集诱导发光增强（AIEE）化合物的 Cu 诱导自组装和 HS 诱导解组装。合成并表征了两种水杨醛缩氨Schiff 碱。研究发现，化合物 1 和 2 在水相和晶体状态下均具有 AIEE 活性，表现出强黄色荧光。它们的荧光可以在 Cu 离子存在下选择性猝灭，形成自组装体系 [1-Cu]。通过多种手段研究了相互作用机制。根据这一反应，还通过 Scatchard 公式估算了从 1 到 [1-Cu] 的能量变化 (ΔG)。此外，HS 可以进一步恢复管内和活细胞中的猝灭荧光，同时释放 AIEE 分子 1。也就是说，在模型化合物中可以发现 AIEE、自组装和解组装之间的可逆过程。
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