Department of Surgery, Elisabeth - TweeSteden Hospital, Dr. Deelenlaan 5, 5042 AD, Tilburg, the Netherlands.
Department of Anaesthesiology, Elisabeth - TweeSteden Hospital, Tilburg, the Netherlands.
J Gastrointest Surg. 2018 Oct;22(10):1779-1784. doi: 10.1007/s11605-018-3836-4. Epub 2018 Jun 25.
There is no consensus as to the effects of epidural analgesia on postoperative outcomes after laparoscopy in the context of the Enhanced Recovery Programs. The aim of this study was to evaluate the effects of epidural analgesia on postoperative outcomes after elective laparoscopic sigmoidectomy.
The use of epidural analgesia was discontinued in elective laparoscopic sigmoidectomy and substituted by the perioperative administration of systemic lidocaine. Data from patients undergoing elective laparoscopic sigmoidectomy between January 2014 and September 2016 was prospectively analysed. Patients with epidural analgesia were compared with patients without, in analgesics administrated postoperatively, length of stay, day of first defecation and mobilisation, and complication and reoperation rates.
A total of 160 patients (male 85; female 75), median age 68 (30-92 years), were included. The groups consisted of 80 patients each. Mean length of stay (5.6 vs. 7.2 days, p = 0.03) and day of first mobilisation (mean 1.2 vs. 1.6 days, p = 0.004) were significantly shorter in the group without epidural analgesia. Reoperation rate (7.5 vs. 2.5%) was not statistically different. Complication rate was significantly lower (12.5 vs. 30%, p = 0.007) in the group without epidural. Day of first defecation was shorter in the epidural group (1.4 vs. 1.7 days, p = 0.04). Mean amount of analgesics administrated was not statistically different between groups, except for metamizole, that was administrated more in the group without epidural.
Epidural analgesia did not offer benefits on postoperative analgesia or outcomes after elective laparoscopic sigmoidectomy, causing longer length of stay, later mobilisation and higher complication rate.
在强化康复计划的背景下,对于腹腔镜手术后硬膜外镇痛对术后结果的影响,尚无共识。本研究旨在评估硬膜外镇痛对择期腹腔镜乙状结肠切除术术后结果的影响。
在择期腹腔镜乙状结肠切除术中停止使用硬膜外镇痛,并代之以围手术期给予全身利多卡因。前瞻性分析 2014 年 1 月至 2016 年 9 月期间行择期腹腔镜乙状结肠切除术的患者数据。将接受硬膜外镇痛的患者与未接受的患者进行比较,比较内容为术后使用的镇痛药、住院时间、首次排便和活动时间、并发症和再次手术率。
共纳入 160 例患者(男性 85 例;女性 75 例),中位年龄 68(30-92 岁),每组 80 例。与无硬膜外镇痛组相比,无硬膜外镇痛组的平均住院时间(5.6 天 vs. 7.2 天,p=0.03)和首次活动时间(平均 1.2 天 vs. 1.6 天,p=0.004)明显缩短。再次手术率(7.5% vs. 2.5%)无统计学差异。并发症发生率明显较低(12.5% vs. 30%,p=0.007)。无硬膜外镇痛组首次排便时间较短(1.4 天 vs. 1.7 天,p=0.04)。两组间镇痛药用量除扑热息痛外无统计学差异,无硬膜外镇痛组扑热息痛用量较多。
硬膜外镇痛并未为择期腹腔镜乙状结肠切除术的术后镇痛或结果带来益处,反而导致住院时间延长、活动时间推迟和并发症发生率升高。