糖尿病患者神经传导速度及其与腱反射（T反射）关系的研究

A Study of Nerve Conduction Velocity in Diabetic Patients and its Relationship with Tendon Reflexes (T-Reflex).

作者信息

Tehrani Khadijeh Haji Naghi

机构信息

Department Neurology, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran.

出版信息

Open Access Maced J Med Sci. 2018 Jun 17;6(6):1072-1076. doi: 10.3889/oamjms.2018.262. eCollection 2018 Jun 20.

DOI:10.3889/oamjms.2018.262

PMID:29983804

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6026439/

Abstract

BACKGROUND

Neuropathy is one of the most common complications of diabetes mellitus. Neuropathy can cause the sensory deficit, neurological disorder, limb ulcers, osteomyelitis, and amputation. Therefore, neurological examinations, determining the nerve conduction velocity and performing sensory and motor tests are important for timely diagnosis and treatment.

AIM

The present study aimed to investigate the nerve conduction velocity in diabetic patients and its relationship with tendon reflexes.

MATERIAL AND METHODS

The present study was observational-cross sectional research carried out on 77 diabetic patients who were admitted into the EMG/NCV Department of Shariati Hospital in the academic year 1996-1997. In all patients, the medical history of the patient (age, duration of diabetes, gender and age of onset of diabetes), neurological examination, nerve conduction velocity, heat test, vibration test, tendon reflexes, D.L and Amplitude were examined and recorded. Finally, the raw data obtained were entered into the IBM SPSS Statistics software, and the important relationships between these variables were analysed. Moreover, in the present study, the statistical significance level (P-value) was considered less than 0.05.

RESULTS

The present study was conducted on a population consisting of 48 women and 29 men with diabetes. The age range of participants was 14-70 years old with an average age of 50.506 ± 7.50. The results of present study showed that the participants with clinical neuropathy (11.2 ± 7.2) had a significantly longer duration of diabetes than the normal group and those participants with sub-clinical neuropathy (P-value = 0.12). Statistical analyses indicated that increase in age, increase in the duration of diabetes and the gender of male significantly made the nerve conduction velocity abnormal. The analysis of the response to neural reflexes indicated that the ratio of neurological disorders in the five nerves of the ankle and knee was generally higher in the abnormal group (the patients with nerve conduction disorder) compared to the normal (the patients with normal nerve conduction) and in some cases, such as the ulnar motor nerve of ankle (P-value = 0.010), and the ulnar motor nerve of knee motor (P-value = 0.002) and also in the peroneal motor nerve of knee (P-value = 0.003) and the sural sensory nerve of knee (P-value = 0.003), increase in neurological disorders was significant.

CONCLUSION

Increase in age, increase in the duration of diabetes, and the male gender can significantly increase the risk of abnormal nerve conduction velocity.

摘要

背景

神经病变是糖尿病最常见的并发症之一。神经病变可导致感觉缺陷、神经功能障碍、肢体溃疡、骨髓炎和截肢。因此，神经检查、测定神经传导速度以及进行感觉和运动测试对于及时诊断和治疗很重要。

目的

本研究旨在调查糖尿病患者的神经传导速度及其与腱反射的关系。

材料与方法

本研究是一项观察性横断面研究，对1996 - 1997学年在沙里亚蒂医院肌电图/神经传导速度科住院的77例糖尿病患者进行。对所有患者检查并记录其病史（年龄、糖尿病病程、性别和糖尿病发病年龄）、神经检查、神经传导速度、热试验、振动试验、腱反射、波幅和波宽。最后，将获得的原始数据输入IBM SPSS Statistics软件，分析这些变量之间的重要关系。此外，在本研究中，统计学显著性水平（P值）被认为小于0.05。

结果

本研究对48名女性和29名男性糖尿病患者进行。参与者的年龄范围为14 - 70岁，平均年龄为50.506±7.50。本研究结果表明，临床神经病变患者（11.2±7.2）的糖尿病病程明显长于正常组和亚临床神经病变患者（P值 = 0.12）。统计分析表明，年龄增加、糖尿病病程延长和男性性别显著使神经传导速度异常。对神经反射反应的分析表明，与正常组（神经传导正常的患者）相比，异常组（神经传导障碍的患者）踝部和膝部五条神经的神经功能障碍比例总体较高，在某些情况下，如踝部尺神经运动支（P值 = 0.010）、膝部尺神经运动支（P值 = 0.002）以及膝部腓总神经运动支（P值 = 0.003）和膝部腓肠感觉神经（P值 = 0.003），神经功能障碍的增加具有显著性。