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减重手术是否有更好的设计?单吻合口十二指肠转流术的案例。

Is There a Better Design for a Bariatric Procedure? The Case for a Single Anastomosis Duodenal Switch.

机构信息

Department of Surgery, Northwell Health, Lenox Hill Hospital, 100 E 77th Street, New York, NY, 10075, USA.

Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT, 84102, USA.

出版信息

Obes Surg. 2018 Dec;28(12):4077-4086. doi: 10.1007/s11695-018-3535-y.

Abstract

The majority of bariatric surgical stapling procedure concepts were developed prior to the understanding of obesity as an energy storage disease. Conventional treatments did not consider the impact of macronutrients on hormones and glucose variability. Current recommendations suggest diets low in glycemic load, with moderate protein and unsaturated fat. Roux-en-Y gastric bypass promotes glucose variability which can be harmful for health and encourage weight regain. Classic duodenal switch with short common channels may prevent absorption of measurable fat-soluble vitamins and frequently untested essential fatty acids. The purpose of this review is to discuss these factors and explain why single anastomosis duodenal switch reduces glucose variability, allows for absorption of critical fats and fat-soluble vitamins, and has potential to offer better weight loss and metabolic outcomes.

摘要

大多数减重手术缝合程序的概念是在人们了解肥胖是一种能量储存疾病之前提出的。传统的治疗方法没有考虑到宏量营养素对激素和葡萄糖变异性的影响。目前的建议是低糖负荷饮食,适量的蛋白质和不饱和脂肪。Roux-en-Y 胃旁路术会促进葡萄糖变异性,这可能对健康有害,并促使体重反弹。经典的十二指肠转流术加短共同通道可能会阻止可测量的脂溶性维生素和经常未经测试的必需脂肪酸的吸收。本文的目的是讨论这些因素,并解释为什么单吻合口十二指肠转流术可以降低葡萄糖变异性,允许吸收关键脂肪和脂溶性维生素,并有可能提供更好的减肥和代谢效果。

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